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We have 73 Biological Sciences PhD Projects, Programmes & Scholarships for Self-funded Students in Bradford
Biological Sciences PhD Projects, Programmes & Scholarships for Self-funded Students in Bradford
We have 73 Biological Sciences PhD Projects, Programmes & Scholarships for Self-funded Students in Bradford
Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders
The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
Dissecting cell wall glucan function in intercellular signalling and plant environmental interactions
Apply to join the Benitez-Alfonso team in their quest to dissect the mechanisms underpinning the function of beta-1,3 glucan polymers in plant growth and development. Read more
Alpha-synuclein amyloid in Parkinson's disease: using Nanoinjection as a tool to study alpha-synuclein amyloid toxicity inside neurons
Intraneuronal inclusions known as Lewy bodies are a hallmark of Parkinson’s disease. Amyloid fibrils formed by the misfolding of alpha-synuclein are the principal component of Lewy Bodies. Read more
Control and inhibition of virus replication
The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more
Design and Folding of beta barrel membrane proteins
The cell walls of Gram negative bacteria are packed with b-barrel outer membrane proteins (OMPs) whose function are essential for bacterial growth and virulence. Read more
Elucidating the molecular mechanisms of intrinsic antibiotic resistance in bacterial pathogens
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to the average human lifespan. Read more
Muscle function during running
The anatomy of the legs is complex with multiple muscles that are (anatomically) capable of flexing and extending the limb joints. Read more
Biological rhythms and the dopamine system in cognitive dysfunction
Research Group:
Pharmacology and Experimental Therapeutics
Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more
Cellular signalling mechanisms in iPSC-derived cardiovascular cells
Research Group:
Pharmacology and Experimental Therapeutics
Induced pluripotent stem cells (iPSCs) offer an advanced platform for disease modelling, drug discovery, and regenerative therapies. Read more
MAPK signalling pathways regulating the blood brain barrier
Research Group:
Pharmacology and Experimental Therapeutics
We invite applications for a 3-year PhD project to investigate cellular signalling regulating the function of the blood brain barrier. Read more
ERK5 MAPK signalling in Alzheimer’s disease
Research Group:
Pharmacology and Experimental Therapeutics
Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more
Delivery and misdelivery of outer membrane proteins to the BAM complex using cryoEM
The BAM complex folds membrane proteins into the outer membrane of Gram-negative bacteria, proteins whose functions are essential for bacterial viability, pathogenicity and virulence. Read more
Formulation and biopharmaceutical characterisation of novel pro-antibiotics for improved oral permeability
Research Group:
Pharmacology and Experimental Therapeutics
This project is focused on the formulation, synthesis, and biopharmaceutical characterisation of novel pro-antibiotics for improved oral bioavailability. . Read more
Molecular resolution of biomolecular assembly by combining neutron scattering and coarse-grained simulation
Research Group:
School of Physics and Astronomy
This PhD project opportunity is part of an exciting new collaboration between the ISIS neutron and muon facility in Oxfordshire and the University of Leeds to develop new tools for understanding the multiscale structure and hydration of biomolecules. Read more
Synthesis of anticancer alkaloids
Research Group:
Chemistry and Biosciences
Luotonin A is a natural occurring plant alkaloid bearing polycyclic quinazolinone. It has shown inhibitory effect towards topoisomerase I (TP1), an enzyme responsible for antibiotic and anticancer. Read more