Background. The discovery that long non-coding RNAs (lncRNAs) can be translated to produce non-canonical micropeptides has revealed an unexplored extension to the human proteome. Read more
Primary cilia play a fundamental role in cell signalling, acting as sensory cellular antennae for chemical and biomechanical signals, including morphogen signalling pathways implicated in myofibroblast transition, the key driver of tissue fibrosis. Read more
The clinical deployment of antibiotics is undermined by antimicrobial resistance (AMR). Without new agents to treat antibiotic resistant bacterial infections, mortality rates are predicted to reach 10 million people per year by 2050. Read more
The human papillomavirus (HPV) is responsible for 5% of human cancers including cervical, oral and anal cancers. HPV is prevalent in low- and middle-income countries, where access to the HPV vaccine is limited. Read more
In psychiatry, the selection of antipsychotics and antidepressants is led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). Read more
Type 1 diabetes (T1D) results from loss of insulin-producing beta cells in the pancreas, which help to control blood glucose. Some people with T1D experience a complication making it harder to exercise, known as exercise intolerance1. Read more
Applying cutting-edge machine learning to rectal cancer MRI from a tertiary hospital. predicting treatment effect for chemoradiotherapy and immunotherapy. . Read more
Background to the project. Healthcare systems consist of hierarchies of individuals and organisations. For example, in the UK, primary care is made up of patients within general practitioners (GPs), in general practices, within primary care networks (PCNs), in regions (Integrated Care Boards). Read more
Evaluation of human-induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CMs) for cardiotoxicity testing Potentially fatal cardiac arrhythmias such as Torsades des Pointes (TdP) are linked to adverse side-effects of drugs intended as potential treatments for a variety of clinical disorders. Read more
One full scholarship is available at the Leeds Institute of Cardiovascular and Metabolic Medicine. This scholarship is open to UK applicants and covers fees plus maintenance. Read more
The School of Medicine invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2025/26 for the ARCTIC Leeds-Manchester PhD Studentship (Image derived frailty assessment in anal cancer patients). Read more
The award is open to candidates (UK only) who meet the eligibility for a place on a PhD degree at the School of Medicine and are at the appropriate stage of clinical training. . Read more
The award is open to full-time or part-time candidates (UK only) who meet the eligibility for a place on a PhD degree at the School of Medicine and are at the appropriate stage of UK clinical specialty training. . Read more
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more
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