Electron microscopy is ideally suited to the nanoscale imaging and analysis of materials; the spatial resolution and availability of advanced spectroscopic techniques afford the opportunity for detailed structural and compositional investigations.
Eye diseases are a common cause of human disability and many of them are inherited. These include congenital as well as adult-onset conditions and diseases of ageing, and may involve abnormalities at the back of the eye or the anterior eye structures.
Metal Organic Frameworks (MOFs) are porous crystalline materials, constructed by metal ions and organic polyfunctional ligands. They have shown promise in a wide range of applications such as gas storage, chemical separations, catalysis, drug delivery, etc.
PhD students are sought in the School of Computing at the University of Leeds, UK. These studentships form part of a larger collaborative and interdisciplinary project, that currently includes two academics (Dr Thomas Ranner and Professor Netta Cohen), a postdoctoral fellow and three PhD students.
This project will involve developing decellularised biological scaffolds as regenerative replacement grafts for replacement of the ruptured anterior cruciate ligament (ACL), which is becoming increasingly prevalent in younger populations with more active lifestyles.
The function and stability of proteins are intimately linked to their environment and consequently, changes in environmental factors such as pH can trigger conformational changes that in turn modulate protein function.
Astbury Centre for Structural Molecular Biology
Dr E Paci, Prof W B Turnbull
30 September 2019
The ability of protein molecules to stick to cells is crucial for life and disease. The project is based on a novel concept to design adhesive molecules based on multivalence and entropic stabilisation.