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Immunology PhD Projects, Programs & Scholarships in Bradford

We have 12 Immunology PhD Projects, Programs & Scholarships in Bradford

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Bradford  United Kingdom

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We have 12 Immunology PhD Projects, Programs & Scholarships in Bradford

International PhD Academy: Medical Research

The International PhD Academy. Medical Research is based in the Leeds Institute of Medical Research at the University of Leeds, St James's University Hospital Campus. Read more

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

  Research Group: School of Molecular and Cellular Biology
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more

Immunotherapy: Killing Cancer using Dead Virus

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more

Cancer: Developing 3D multicellular tumour spheroid models to assess EPA-oncolytic viruses combination therapies in vitro

Cancer immunotherapy holds significant promise for the treatment of a range of cancers. Immunotherapy efficacy, such therapeutic antibodies and oncolytic viruses (OVs), have been clinically assessed against a range of solid tumours. Read more

Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Using ex-vivo genetic systems as models to detect genetic susceptibility to co-morbidities in Covid 19 infection, and to test specific anti-inflammatory / antiviral drugs in Covid 19 infection

  Research Group: Chemistry and Biosciences
Research has shown that certain individuals are more susceptible to SARS-CoV-2. Approximately, 20–51% of COVID-19 patients presented with a least one co-morbidity on admission, with diabetes (10–20%) hypertension (10–15%) and other cardiovascular and cerebrovascular diseases (7–40%) being most prevalent. Read more

The role of UV exposure and novel compounds on the immunogenicity and genotoxicity of skin cancer

  Research Group: Chemistry and Biosciences
The major aims of this project are to investigate the effect of UV in the development of different skin cancers compared to spontaneously regressing precancerous lesion, keratoacanthoma; and the effect of a novel compounds such as the structurally modified retinoic acid in the treatment of skin cancers and other cutaneous lesions. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
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