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We have 10 Immunology PhD Projects, Programmes & Scholarships in Bradford
Immunology PhD Projects, Programmes & Scholarships in Bradford
We have 10 Immunology PhD Projects, Programmes & Scholarships in Bradford
Cancer: Investigation of accentuated mitochondrial ROS and NLRP3 inflammasome activation in cystic fibrosis and colorectal carcinoma.
Cystic fibrosis (CF) is associated with an accentuated inflammatory response to bacterial lipopolysaccharides (LPS), increased resting energy expenditure and a higher than expected prevalence of gastrointestinal and other malignancies. Read more
Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer
Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more
Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders
The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives
Research Group:
Institute of Cancer Therapeutics
Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance
Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more
Cancer: Complex 3D modelling of the tumour microenvironment for immunotherapy combination screening
Cancer immunotherapy holds significant promise for the treatment of a range of cancers. Read more
Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity
The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more
Immunotherapy: Killing Cancer using Dead Virus
It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more
Haematology: Oncogenic reprogramming of immune cells
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more
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