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Medical / Clinical Science PhD Projects, Programs & Scholarships in Bradford

We have 28 Medical / Clinical Science PhD Projects, Programs & Scholarships in Bradford

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  Epigenetics and Cancer: Development of Novel Tools to Determine how Aberrant V(D)J Recombination Reactions Cause Leukaemia
  Dr J Boyes
Applications accepted all year round
V(D)J recombination generates a highly diverse set of immunoglobulin and T cell receptor genes to enable vertebrates to fight a vast range of infections.
  Healthy ageing and diaphragm dysfunction: neuromuscular causes and implications for exercise tolerance.
  Research Group: School of Biomedical Sciences
  Dr B Taylor, Dr C Ferguson, Dr T.S. Bowen
Application Deadline: 11 March 2019
Normal ageing of the respiratory system involves significant and negative structural changes to the lungs, airways, and respiratory muscles.
  Women with non obstructive coronary artery disease: targeting progression to cardiac events with exercise.
  Research Group: School of Biomedical Sciences
  Prof K M Birch, Dr B Taylor, Dr E Levelt
Application Deadline: 11 March 2019
The Women’s Ischemic Syndrome Evaluation suggest that 3–4 million women and men with signs/symptoms suggestive of myocardial ischemia have no obstructive coronary artery disease (INOCA).
  Targeting addiction to a breast cancer metastasis survival pathway by inhibition of RAN GTPase
  Research Group: Institute of Cancer Therapeutics
  Dr S Shnyder, Prof M El-Tanani, Dr S Betmouni
Applications accepted all year round
Metastatic cancer is a major global health burden. Each year, eleven million new cases of cancer are diagnosed worldwide, including 5 million cases in industrialized countries.
  Re-purposing established drugs for the resolution of pulmonary arterial hypertension (PAH)
  Research Group: Pharmacology and Experimental Therapeutics
  Dr T Nasim
Applications accepted all year round
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death.
  Impact of RhoA deregulation on smooth muscle cell phenotypic dysfunction in Type 2 diabetes
  Research Group: Chemistry and Biosciences
  Dr K Riches-Suman
Applications accepted all year round
Type 2 diabetes (T2D) is an escalating healthcare burden. It inflicts significant physical and emotional distress on patients and their carers, and treatment of T2D and its complications accounts for ~10% of the entire NHS budget.
  Uncovering the mechanisms of skeletal muscle cellular dysfunction in heart failure patients with diabetes
  Research Group: School of Biomedical Sciences
  Dr T.S. Bowen, Dr B Taylor, Dr K.K. Witte
Application Deadline: 11 March 2019
Heart failure (HF) is characterised by exercise intolerance and high mortality – both of which are significantly exacerbated in patients with concomitant type 2 diabetes (DHF).
  Identifying cardiac disease markers using non-lethal ’biopsy’ of cells.
  Research Group: School of Biomedical Sciences
  Dr A.J. Smith
Applications accepted all year round
This project will build on our recent exciting discovery that a novel chemical tool, the polymer styrene maleic acid (SMA), can ‘biopsy’ human vascular cells, extracting proteins from the membrane without killing the cells.
  An integrated approach to the study of cellular interactions with amyloid
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford
Applications accepted all year round
The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
  Characterisation of a pre-osteoblast subset of human mesenchymal stem cells: implications for novel osteoarthritis and osteoporosis treatment development
  Dr E Jones, Prof D McGonagle
Applications accepted all year round
Osteoarthritis (OA) and osteoporosis (OP) are the most common age-related skeletal diseases. They seriously affect patient’s quality of life and represent a significant healthcare burden to the UK society.
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