Globally, nearly 189,000 people die each year as a result of brain cancer and around 250,000 people are diagnosed with a malignant brain tumour (umbrella name. Read more
The growing complexity of health care, the demands of managing multi-morbidity, and increasing availability of clinical guidelines all contribute to pressures on clinical decision-making. Read more
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (including DNA methyltransferase inhibitors, HDAC inhibitors and/or vitamin C), as a potential combination therapy for colorectal cancer (CRC). Read more
Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide. Read more
Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more
Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more
As the COVID-19 pandemic recedes, it has left in its wake a toxic legacy of chronic disease in millions of people world-wide. Termed “Long-COVID”, symptoms include debilitating fatigue, cognitive impairment, pain, respiratory and cardiovascular issues. Read more
In psychiatry, the selection of antipsychotics and antidepressants is led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). Read more
This fully funded PhD scholarship provides an exciting opportunity to pursue postgraduate research in the field of child and adolescent obesity and mental health. Read more
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