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Molecular Biology PhD Projects, Programs & Scholarships in Bradford

We have 35 Molecular Biology PhD Projects, Programs & Scholarships in Bradford

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  Structural and Biophysical Characterisation of Novel Membrane Protein Ion Channels (Chinese candidates / China mainland only)
  Research Group: School of Biomedical Sciences
  Dr C Pliotas
Application Deadline: 8 January 2020

Funding Type

PhD Type

Research in the Pliotas group (https://www.pliotasgroup.org/) focuses on the investigation of molecular mechanisms which underlie the structure and function of integral membrane proteins, in particular ion channels.
  Sociobiology on the fly; understanding social interactions in multispecies groups
  Research Group: School of Biology
  Dr A Bretman, Dr X Harrison
Application Deadline: 6 January 2020

Funding Type

PhD Type

The effects of social environments on individuals are widespread, even in species not classically thought of as social (Bailey and Moore 2018).
  Development of a treatment for drug-resistant childhood epilepsy caused by potassium channel dysfunction.
  Dr J D Lippiat, Dr S Clapcote, Dr S Muench
Applications accepted all year round

Funding Type

PhD Type

Gain-of-function mutations in the human gene KCNT1, which encodes the KNa1.1 sodium-activated potassium channel, cause severe childhood epilepsy that cannot be controlled by current medication.
  Reconfigurable Polymers via Supramolecular Self-Sorting
  Prof A J Wilson
Applications accepted all year round

Funding Type

PhD Type

The goal of this project is to mimic the ability of biological materials to force macromolecular reconfiguration using photo-switchable non-covalent self-sorting.
  Developing pluripotent stem cell models of inherited retinal diseases
  Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Background. Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide.
  Exploring the mitotic functions of ASPM in human brain size regulation
  Dr J Bond, Dr E E Morrison, Prof M Peckham
Applications accepted all year round

Funding Type

PhD Type

The increase in relative brain size is one of the most striking events in human evolution. To determine how human brain size is normally regulated we have investigated the cause of autosomal recessive primary microcephaly (MCPH), a congenital disorder of reduced brain size and associated mental retardation.
  Genetic studies of corneal endothelial dystrophies and development of alternative treatment options
  Dr M Ali
Applications accepted all year round

Funding Type

PhD Type

The cornea is the protective front part of the eye that provides most of the eyes focusing power. The endothelium is a single-cell layer on the inside of the cornea that maintains fluid balance and is required for corneal transparency.
  Enhancing Oncolytic Virus-induced Immunotherapy using Eicosapentaenoic Acid (EPA)
  Dr F Errington-Mais, Dr MA Volpato
Applications accepted all year round

Funding Type

PhD Type

Breast cancer is the most commonly diagnosed cancer in women with triple-negative breast cancer (TNBC) having the worst prognosis, highest death rate and lowest overall survival.
  Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
  Dr E Valleley, Dr L Coletta
Applications accepted all year round

Funding Type

PhD Type

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (such as DNA methyltransferase inhibitors), as a potential combination therapy for colorectal cancer (CRC).
  The functional characterization of the tumour suppressor gene CSMD1 in breast cancer
  Dr S Bell
Applications accepted all year round

Funding Type

PhD Type

CUB and Sushi multiple domains protein 1 (CSMD1) maps to 8p23, a region deleted in many cancers including breast cancer. Our previous work has established that CSMD1 is an independent prognostic marker in ductal breast cancer, with reduced expression associated with high tumour grade and poor survival1.
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