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We have 24 Molecular Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Bradford

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Bradford  United Kingdom

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Molecular Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Bradford

We have 24 Molecular Biology PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Bradford

Studying a PhD in Molecular Biology would provide you with the chance to guide your own research project. With a strong link to Cell Biology, Molecular Biology projects revolve around understanding the composition, structure, and interaction of molecules within the cell that control its function. These are generally laboratory-based projects.

What’s it like to do a PhD in Molecular Biology?

As a PhD student in Molecular Biology, you’ll develop extensive laboratory skills including DNA sequencing, expression cloning, gene knockout, and DNA or protein arrays. Your understanding of the range of techniques available to you will continually improve as you’ll read the latest publications in the field.

Some typical research topics in Molecular Biology include:

  • Understanding the role of a certain protein within a cell
  • Investigating DNA repair mechanisms and potential faults
  • Studying the difference in post-translational modifications in response to stimuli
  • Development of novel therapeutics
  • Investigating how proteins act differently in a disease
  • Studying DNA replication

A majority of Molecular Biology projects are proposed in advance by the supervisor and are advertised on the university website. Some of these projects are fully-funded by the university or a doctoral training programme, while others require you to self-fund.

Suggesting a project for yourself is uncommon in Molecular Biology, due to the challenge of finding funding to cover PhD and bench fees, as well as having to find a supervisor with suitable equipment and research interests to support your project.

Day-to-day, you’ll be in the laboratory preparing or conducting experiments, analysing previous data, creating figures, and writing up the results, alongside quick chats with your colleagues and supervisors about your work.

In the final year of your PhD, you’ll complete an original thesis of approximately 60,000 words in length and give an oral defence of this during a viva exam.

Entry requirements

The entry requirements for most Molecular Biology PhD programmes involve a Masters in a subject directly related to Biology, with at least a Merit or Distinction. If English isn’t your first language, you’ll also need to show that you have the right level of language proficiency.

PhD in Molecular Biology funding options

The research council responsible for funding Molecular Biology PhDs in the UK is the Biotechnology and Biological Sciences Research Council (BBSRC). They provide fully-funded studentships including a stipend for living costs, a consumables budget for bench fees and a tuition fee waiver. Students don’t apply directly to the BBSRC, you apply for advertised projects with this funding attached.

It’s uncommon for Molecular Biology PhD students to be ‘self-funded’ due to the additional bench fees. However, if you were planning to fund yourself it might be achievable (depending on your project) through the UK government’s PhD loan and part-time work.

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Control and inhibition of virus replication

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Epigenetic regulation of skin wound healing

  Research Group: Chemistry and Biosciences
Skin in the largest organ in the human body consisting of epidermis, dermis and subcutis. It also contains epithelial appendages, including hair follicles and sweat glands. Read more

Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

  Research Group: School of Molecular and Cellular Biology
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Cancer: Epigenetic therapy using microbubble-mediated drug delivery for colorectal cancer

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (including DNA methyltransferase inhibitors, HDAC inhibitors and/or vitamin C), as a potential combination therapy for colorectal cancer (CRC). Read more

Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

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