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Pathology PhD Projects, Programs & Scholarships in Bradford

We have 9 Pathology PhD Projects, Programs & Scholarships in Bradford

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Showing 1 to 9 of 9
  Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
  Dr S Papa
Applications accepted all year round
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow.
  An integrated approach to the study of cellular interactions with amyloid
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford
Applications accepted all year round
The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
  How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
  Prof C Inglehearn
Applications accepted all year round
Amelogenesis is the process of enamel formation and is essential for the development of functional teeth. Amelogenesis imperfecta (AI) is a failure of that process.
  The genetic basis of cognitive impairment in intellectual disability and schizophrenia
  Prof C Inglehearn, Dr M Ali
Applications accepted all year round
Schizophrenia is a chronic mental health condition affecting 1% of human populations, with symptoms that include visual and auditory hallucinations, delusions and disordered thought, leading to disruption of the sense of self.
  Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
  Prof C Inglehearn
Applications accepted all year round
Human inherited retinal dystrophies (IRDs) result from mutations in over 200 different genes, many of them first implicated by the Leeds Vision Research Group (eg Panagiotou E et al 2017, AJHG 100:960-968; El-Asrag M et al 2015, 96:948-54).
  Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
  Dr S Bell, Prof C A Johnson
Applications accepted all year round
Women who have undergone surgery for breast and ovarian cancer often have additional chemotherapy to kill residual cancer cells and prevent recurrence.
  Understanding drug-resistance in myeloid cancer
  Dr P Laslo
Applications accepted all year round
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory.
  Electrophysiological changes in ion channels in human haploid and diploid (spermatozoa and lymphocytes) after nanoparticle exposure
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr M H Brinkworth, Prof D Anderson
Applications accepted all year round
Nanomaterial-mediated delivery represents a promising technique for repro- and geno- toxicology with a potential to improve the safety and efficacy of existing methodologies, including experimental gene therapy and sperm-mediated gene transfer.
  Defining active immunoprotection and regulatory T cell promotion in hair follicles
  Research Group: Centre for Skin Sciences
  Prof K McElwee, Dr N Botchkareva
Applications accepted all year round
In the non-scarring inflammatory hair loss disease Alopecia areata (AA) lymphocytes specifically target hair follicles (HFs) and disrupt hair growth.
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