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Pharmacy / Pharmaceutics PhD Projects, Programs & Scholarships in Bradford
We have 26 Pharmacy / Pharmaceutics PhD Projects, Programs & Scholarships in Bradford
We have 26 Pharmacy / Pharmaceutics PhD Projects, Programs & Scholarships in Bradford
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Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases
Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more
Development of antibody-drug conjugates (ADCs) for oncology indications
Research Group:
Institute of Cancer Therapeutics
A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more
Formulation of heterogenous solid dispersions produced by spray drying and hot-melt extrusion for improved delivery of amorphous drugs
Research Group:
Pharmacology and Experimental Therapeutics
Production of the amorphous solid dispersions (ASDs) is a one of the methods of improving of physicochemical properties of an active pharmaceutical ingredient (API) such as its solubility and physicochemical stability. Read more
Formulation and biopharmaceutical characterisation of novel pro-antibiotics for improved oral permeability
Research Group:
Medicines Development and Pharmaceutical Sciences
This project is focused on the formulation, synthesis, and biopharmaceutical characterisation of novel pro-antibiotics for improved oral bioavailability. Read more
ERK5 MAPK signalling in Alzheimer’s disease
Research Group:
Pharmacology and Experimental Therapeutics
Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more
Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer
Research Group:
Institute of Cancer Therapeutics
Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more
Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives
Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more
Development of a personalized therapy for pulmonary arterial hypertension (PAH)
Research Group:
Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more
Determining brain glycosylation in ageing and Alzheimer’s disease
Research Group:
Pharmacology and Experimental Therapeutics
Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Biodegradable composite materials (Bio-PolyMOFs) for applications in targeted delivery of drugs to improve healthcare and reduce antimicrobial resistance in developing countries and worldwide
Research Group:
Chemistry and Biosciences
Growing antimicrobial resistance (AMR) is one of the major global challenges and is linked to the use of unnecessarily high doses of orally administered antibiotics following medical surgery and infections. Read more
An assessment of professional burnout within the pharmacist profession: A comparative study of Kuwait and the UK
Research Group:
Medicines Optimisation
Depression or nervous breakdown were originally used to express professional exhaustion resulted from stress until the 1970s when Freudenberger introduced burnout as a clinical complex to replace those terms (Felton, 1998). Read more
Investigation into the in-vitro lung deposition of liposomal formulations of the dual fixed-dose combination inhaler
Research Group:
Medicines Development and Pharmaceutical Sciences
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are diseases associated with the airflow in the lungs (WHO, 2013). Inhalation is the most effective route of administration for treating asthma and COPD (Labiris and Dolovich, 2003). Read more
Therapeutic resolution of BMPR2-mediated signalling defects in pulmonary arterial hypertension (PAH)
Research Group:
Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is an incurable and devastating disease and death occurs within 2.5 years of diagnosis. Read more
Novel nanoparticle-loaded formulations to enhance the locoregional delivery of anticancer drugs to brain tumours
Research Group:
School of Physics and Astronomy
Glioblastoma (GBM) is the deadliest form of primary brain tumour with an extremely poor survival duration of less than 15 months. Read more
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