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We have 25 Pharmacy PhD Projects, Programmes & Scholarships in Bradford
Pharmacy PhD Projects, Programmes & Scholarships in Bradford
We have 25 Pharmacy PhD Projects, Programmes & Scholarships in Bradford
Re-purposing established drugs for the resolution of pulmonary arterial hypertension (PAH)
Research Group:
Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more
Exploring chemoprevention: Investigating the impact of novel Endocrine Disrupting Chemicals (EDCs) on breast cells and onset of tumours using a Body-on-a-chip model
Research Group:
Institute of Cancer Therapeutics
Endocrine-disrupting compounds (EDCs) are a group of chemicals that can alter the normal functioning of the body’s hormonal system and can have harmful effects. Read more
Computational and machine learning driven development of new polysialyltransferase (ST8SiaII) inhibitors against metastatic cancer
Research Group:
Institute of Cancer Therapeutics
Polysialic acid (polySia) is a carbohydrate polymer important for embryonic development. PolySia is absent in healthy adult tissues whereas overexpressed in several tumours. Read more
Optimising technology-related medication management in home care settings for older adults using a mixed-methods approach
With a rapidly ageing population in the UK, there is an escalating demand for home care and the use of technologies in delivering such care. Read more
Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia
Research Group:
Pharmacology and Experimental Therapeutics
Dementia describes a group of age-associated conditions of which cognitive decline is a major feature. Alzheimer’s disease (AD) is the most common cause of dementia and is characterised by the onset of a gradual cognitive decline. Read more
Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer
Research Group:
Institute of Cancer Therapeutics
Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more
Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives
Research Group:
Institute of Cancer Therapeutics
Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Therapeutic resolution of BMPR2-mediated signalling defects in pulmonary arterial hypertension (PAH)
Research Group:
Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is an incurable and devastating disease and death occurs within 2.5 years of diagnosis. Read more
Integrated omics approach to psychiatric disorders
Research Group:
Chemistry and Biosciences
In psychiatry, the selection of antipsychotics and antidepressants is led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). Read more
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