Neurodegenerative diseases of ageing such as Alzheimer’s and Parkinson’s diseases (AD and PD) have a huge societal and financial impact yet cost-effective therapies to delay or cure these diseases are lacking. Read more
Neurodegenerative diseases of ageing such as Alzheimer’s and Parkinson’s diseases (AD and PD) have a huge societal and financial impact yet cost-effective therapies to delay or cure these diseases are lacking. Read more
Many viruses infect cells by hijacking cellular trafficking pathways, beginning by using their external spikes to bind specific receptor molecules on the cell surface. Read more
Many viruses infect cells by hijacking cellular trafficking pathways, beginning by using their external spikes to bind specific receptor molecules on the cell surface. Read more
Our research aims to understand and manipulate plant DNA-repair pathways. This project elucidates the molecular mechanism of non-homologous end joining (NHEJ) for double-strand break (DSB) repair in Arabidopsis. Read more
Membrane proteins are crucial to cellular function, such as recognition of – and interaction with – the extracellular environment and neighbouring cells, and controlling membrane dynamics, cellular signalling and transport of molecules and ions across membranes. Read more
The clinical deployment of antibiotics is undermined by antimicrobial resistance (AMR). Without new agents to treat antibiotic resistant bacterial infections, mortality rates are predicted to reach 10 million people per year by 2050. Read more
The clinical deployment of antibiotics is undermined by antimicrobial resistance (AMR). Without new agents to treat antibiotic resistant bacterial infections, mortality rates are predicted to reach 10 million people per year by 2050. Read more
Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are characterised by the accumulation and spread of ⍺-synuclein filaments in the brain. Read more
Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are characterised by the accumulation and spread of ⍺-synuclein filaments in the brain. Read more
The cuticle of plant leaf, functionalised by a hydrophobic micro-structured layer of wax, is a complex composite material that regulates interactions with natural and synthetic fluidic resources. Read more
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