The clinical deployment of antibiotics is undermined by antimicrobial resistance (AMR). Without new agents to treat antibiotic resistant bacterial infections, mortality rates are predicted to reach 10 million people per year by 2050. Read more
Research Group:
School of Molecular and Cellular Biology
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more
The aim of this PhD project is to determine the in situ 3D molecular structures associated with AD to understand disease mechanisms and molecular pathways that can lead to the rational design of a mechanism-based therapy. Read more
Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are characterised by the accumulation and spread of ⍺-synuclein filaments in the brain. Read more
Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are characterised by the accumulation and spread of ⍺-synuclein filaments in the brain. Read more
The cuticle of plant leaf, functionalised by a hydrophobic micro-structured layer of wax, is a complex composite material that regulates interactions with natural and synthetic fluidic resources. Read more
Background. The antibiotic fusidic acid (FA) blocks bacterial protein synthesis by interacting with Elongation-factor G (EF-G). Resistance to FA is caused by FusB, which interacts with EF-G, altering its motion. Read more
The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
We are seeking an enthusiastic PhD student to join our exciting project on developing novel fluorinated glycan probes to study glycan-binding proteins (GBPs). Read more
Glycans are sugar-based molecules which play an important role in biological processes ranging from cell-cell communication to energy metabolism. Read more
Many plant derived compounds (phytochemicals) have been developed into pharmaceutical drugs. Many other phytochemicals in the modern diet exert potent biological effects on the human body. Read more
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