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We have 11 Toxicology PhD Projects, Programmes & Scholarships in Bradford

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Toxicology PhD Projects, Programmes & Scholarships in Bradford

We have 11 Toxicology PhD Projects, Programmes & Scholarships in Bradford

University of Bradford

Making Knowledge Work at the University of Bradford

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Investigating molecular determinants of cellular fate driven by air pollutants

University of Bradford
Faculty of Life Sciences
Air pollution is a critical global issue with severe consequences for the environment, economy, and human health. 99% of the world’s population lives in areas where air pollution exceeds WHO guidelines, leading to accelerated ageing, increased mortality, and decreased health span [1,2,3]. . Read more
 Supervisors: Dr J Elies Gomez, Dr ED Perkins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more
 Supervisors: Dr S Shnyder, Dr S Kantamneni
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Formulation of heterogenous solid dispersions produced by spray drying and hot-melt extrusion for improved delivery of amorphous drugs

University of Bradford
Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Production of the amorphous solid dispersions (ASDs) is a one of the methods of improving of physicochemical properties of an active pharmaceutical ingredient (API) such as its solubility and physicochemical stability. Read more
 Supervisors: Dr K Paluch, Dr M Isreb
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more
 Supervisors: Dr J Muller, Prof R Falconer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

University of Bradford
Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more
 Supervisors: Dr T Nasim, Prof C Wright
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

University of Bradford
Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more
 Supervisors: Dr T Nasim, Dr M Najafzadeh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more
 Supervisors: Dr S Shnyder, Prof S El-Khamisy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Re-purposing established drugs for the resolution of pulmonary arterial hypertension (PAH)

University of Bradford
Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more
 Supervisors: Dr T Nasim, Dr K Assi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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