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We have 137 PhD Projects, Programmes & Scholarships in Bristol

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Bristol  United Kingdom

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PhD Projects, Programmes & Scholarships in Bristol

We have 137 PhD Projects, Programmes & Scholarships in Bristol

Identifying causal pathways to disease using DNA methylation predicted blood traits.

Project Background. Blood cell types have been implicated in pathogenesis of chronic diseases. Genome wide association studies have identified thousands of variants associated with blood trait variation. Read more

Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more

The use of life course epidemiology to support the experimental characterisation of genetic variation

Project Background. There has been a rapid expansion in the generation of genetic sequence data over the last decade. Understanding the potential relevance of genetic mutations to human health remains challenging. Read more

Metabolomic characterisation of adiposity across the life course

Project Background. There is evidence that adiposity, measured by body mass index (BMI), causally influences a range of health outcomes, but little understanding of the mechanisms driving BMI effects. Read more

MScR - Preserving t-tubule function in adult cardiac myocytes in short-term culture

Invaginations of the sarcolemma of adult cardiac myocytes known as transverse (or t-) tubules account for up to 65% of the total sarcolemma surface and play a key role in excitation-contraction (EC) coupling and cell signalling (Hong & Shaw, 2017). Read more
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Synthetic Carbohydrate Receptors with Medical Applications

A PhD studentship funded through a UKRI Frontier Research Grant (selected as an ERC Advanced Grant) is available in the group of Prof. Read more

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