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We have 15 Biochemistry PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Bristol

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Bristol  United Kingdom

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Biochemistry PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Bristol

We have 15 Biochemistry PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Bristol

A PhD in Biochemistry would provide you with the time and resources to undertake an in-depth research project into one area of biochemistry. These projects are almost always laboratory-based and can range from investigating the structure and role of a protein or receptor to developing and optimising current detection methods.

What’s it like to do a PhD in Biochemistry?

Doing a PhD in Biochemistry, you’ll develop wide-spread laboratory skills including protein purification, western blotting, chromatography, and polymerase chain reaction (PCR). The use of cutting-edge equipment such as nuclear magnetic resonance (NMR) is common in Biochemistry and consequently you’ll become proficient with these fine instruments.

Some typical research topics in Biochemistry include:

  • Engineering enzymes for industry
  • Characterising the structure and function of proteins
  • Developing novel therapeutics
  • Understanding the role of redox in a system or disease
  • Investigation of a specific receptor
  • Developing and optimising methods (such as NMR)

Day-to-day you’ll be in the laboratory performing experiments, writing up and analysing data from previous experiments and discussing your results and research plans with colleagues.

Biochemistry programmes are almost always advertised research projects, with the key aim pre-determined by the supervisor. Although the aim is set, you are still free to influence the direction of the project along the way. These advertised programmes usually come with full funding attached.

It is uncommon to propose your own research in Biochemistry as you must find a supervisor with research goals that overlap with your project, who also has adequate equipment for your experimental work, and you must find sufficient funding for bench and PhD fees.

Regardless of being funded or not, your PhD will end with a thesis of around 60,000 words, which contributes significantly to the knowledge of the field. To be awarded your PhD, you’ll then need to defend your thesis during your viva exam.

Entry requirements

The entry requirements for most Biochemistry PhD programmes involve a Masters in a subject directly related to Biochemistry such as Biology or Chemistry, with at least a Merit or Distinction. If English isn’t your first language, you’ll also need to show that you have the right level of language proficiency.

PhD in Biochemistry funding options

The Research Council responsible for funding Biochemistry PhDs in the UK is the Biotechnology and Biological Sciences Research Council (BBSRC). They provide fully-funded studentships including a stipend for living costs, a consumables budget for bench fees and a tuition fee waiver. Students don’t apply directly to the BBSRC, you apply for advertised projects with this funding attached.

It’s uncommon for Biochemistry PhD students to be ‘self-funded’ due to the additional bench fees. However, if you were planning to fund yourself it might be achievable (depending on your project) through the UK government’s PhD loan and part-time work.

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MScR: Interplay of chromatin remodelling and maintenance of genome stability

Genome instability is a known driver of tumourigenesis and hallmark of cancer. Efficient eukaryotic DNA repair requires changes to chromatin to allow signalling and access of repair proteins to sites of damage. Read more

MScR: Dynamic cell and tissue responses to damage: understanding tissue repair and inflammation

Our lab is interested in the fundamental mechanisms used by cells and tissues to recover from damage. The ability to rapidly repair after injury is a key feature of many tissues, including the skin. Read more

Understanding the molecular mechanism of a novel innate bacterial defence system and its synergy with CRISPR-Cas

Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well‐studied of which are the Restriction‐Modification and the CRISPR‐Cas enzymes. Read more

MScR: Understanding Cell Biology Through Imaging

We study the trafficking and interaction of molecules and structures inside cells. Extracellular signals need to be processed in a correct manner for a cell to function properly. Read more

Re-engineering Golgi dynamics in plants – investigating the role of myosin receptors

The growing global population requires the development of novel strategies to sustainably increase food production. Organelle movement is dynamic and linked to changes in cell size, plant biomass and in response to factors which affect food production such as pathogens (Perico and Sparkes, New Phytol. Read more

Integrated multi-omics characterisation of human retroviral reservoirs

About the Project. Human retroviruses are a group of pathogens infecting an estimated 50 million people worldwide. The most widespread human retrovirus is HIV-1, which remains a major cause of morbidity and mortality, particularly in developing countries. Read more

Tissue-engineering constructs suitable for reconstructive cardiac surgery in patients with congenital heart defect

Congenital heart defects (CHD) are the primary cause of infant deaths in Europe and North America. The primary treatment for CHD is surgery but the major problem with surgery for such defects is the lack of living replacement materials with the capacity of growth and regeneration. Read more

Dynamic cell and tissue responses to damage: understanding tissue repair and inflammation

Our lab is interested in the fundamental mechanisms used by cells and tissues to recover from damage. The ability to rapidly repair after injury is a key feature of many tissues, including the skin. Read more

SynBac: Synthetic Baculovirus Genomes for Next-generation Drug Discovery and Gene Therapy

Baculovirus is a highly efficient delivery system for recombinant genes into eukaryotic cells, with great impact on the production of eukaryotic proteins, including high-value drug targets for pharmaceutical development. Read more

Understanding Cell Biology through Imaging

We study the trafficking and interaction of molecules and structures inside cells. Extracellular signals need to be processed in a correct manner for a cell to function properly. Read more

Role of the Rho GTPase RhoD in cancer

Epithelial cancers such as breast cancer become difficult to treat when they invade the surrounding tissues, eventually entering the blood stream and spreading to other parts of the body to form metastases. Read more

Mechanisms of cancer cell invasion

Epithelial cancers such as breast cancer become difficult to treat when they invade the surrounding tissues, eventually entering the blood stream and spreading to other parts of the body to form metastases. Read more

MScR: Role of the Rho GTPase RhoD in breast cancer

Epithelial cancers such as breast cancer become difficult to treat when they invade the surrounding tissues, eventually entering the blood stream and spreading to other parts of the body to form metastases. Read more
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