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Genetics PhD Projects, Programs & Scholarships in Bristol

We have 9 Genetics PhD Projects, Programs & Scholarships in Bristol

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Bristol  United Kingdom

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We have 9 Genetics PhD Projects, Programs & Scholarships in Bristol

Effects of transcription on genome stability

Transcription-coupled DNA repair (TCR) pathways prioritise the repair of certain lesions in "active" genes. These pathways help maintain genome integrity throughout the lifetime of multi-cellular organisms, and thus help prevent the occurrence of mutation that might cause cancer or other disorders. Read more

Expanding the range of inference and estimation in Multivariable Mendelian Randomization

Many of an individual’s traits and characteristics are observationally associated with their health outcomes, however these relationships are often confounded, meaning it is not possible to determine the causal effect of particular traits on different outcomes. Read more

Investigating intracellular signalling mechanisms in the hippocampus: implications in memory formation and disease

Rationale. MicroRNAs (miRNA) are non-coding RNAs that mediate the silencing of specific messenger RNAs. miRNAs are involved in the regulation of all cellular processes and they are particularly important in coordinating gene expression and function in neurons (1). Read more

Investigating the role of the regulatory renin-angiotensin system in protecting against synaptic dysfunction in Alzheimer’s disease

Rationale. Mid-life hypertension is a modifiable risk factor for Alzheimer’s disease (AD) and blood pressure lowering drugs, especially those that target the brain renin-angiotensin system (RAS), lowers the incidence of AD, and reduces the conversion of MCI and slows the progression of AD. Read more
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