Summary. Cytotoxic T cells have the capability of killing tumour target cells. However, this ability is commonly suppressed within the tumour microenvironment. Read more
Cancer arises in part from intrinsic molecular and cellular alterations. For instance, loss of major DNA damage response genes such as BRCA1/2 has long been known to predispose individuals to multiple cancer types. Read more
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
The project. Upper airway obstructions (‘wind problems’) affect the health, welfare and performance of racehorses and are best evaluated by performing endoscopy, however, assessment is subjective, attracting variable agreement. Read more
Sudden cardiac death (SCD) is an important clinical problem and has a lasting impact on relatives of the deceased, particularly when sudden death occurs… Read more
What makes one neuron different from another? How can we define different “types” of cells? Are cell types important?. In Parkinson’s disease some dopamine neurons seem to be more vulnerable to neurodegeneration. Read more
Invaginations of the sarcolemma of adult cardiac myocytes known as transverse (or t-) tubules account for up to 65% of the total sarcolemma surface and play a key role in excitation-contraction (EC) coupling and cell signalling (Hong & Shaw, 2017). Read more
A significant fraction of patients affected by Long COVID, long-term consequences following acute SARS-CoV-2 infection, suffer from mental fatigue and cognitive deficits (1-3). Read more
It is now firmly established that in the mammalian brain neuronal networks cannot successfully perform their functions without concomitant metabolic and signalling support from the adjacent glial cells, called astrocytes. Read more
It has become increasingly clear that ‘neuro’science research must consider the roles of non-neuronal cells in the central nervous system if integrated brain function is to be ultimately understood. Read more
We are seeking an enthusiastic health researcher or social scientist with skills in qualitative methods, health research or health psychology to join the next generation of inter-disciplinary researchers who will improve people's health through developing new approaches for improving surgical outcomes. Read more
The effect of COVID-19 on lower urinary tract function. An opportunity to apply for a funded full-time PhD in the College of Health, Science and Society, UWE Bristol. The studentship will be funded by UWE Bristol. Read more
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
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