We have 69 Medicine PhD Projects, Programmes & Scholarships in Bristol

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Medicine

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Bristol  United Kingdom

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Medicine PhD Projects, Programmes & Scholarships in Bristol

We have 69 Medicine PhD Projects, Programmes & Scholarships in Bristol

Identifying DNA methylation signatures of prostate cancer progression and mortality among patients with clinically confirmed, localised disease at baseline in a large prospective clinical trial

Rationale. Prostate Cancer (PCa) is a leading cause of male mortality, with 336,000 deaths worldwide each year (1). Although most PCa cases are indolent, slow-growing, and tend not to progress, a subset of PCa cases are more aggressive and will progress to metastases, treatment resistance and death. Read more

Identifying causal pathways to disease using DNA methylation predicted blood traits.

Project Background. Blood cell types have been implicated in pathogenesis of chronic diseases. Genome wide association studies have identified thousands of variants associated with blood trait variation. Read more

How does parental education increase risk to ADHD in the offspring?

Rationale. Attention Deficit Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental condition, characterised by persistent difficulties in the areas of attention span/impulse control. Read more

Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

Project Background. Genome wide association studies (GWAS) have discovered many genetic associations with health outcomes. However, most GWAS signals reside in non-coding regions and it is likely that GWAS variants confer their effects through a regulatory mechanism. Read more

Estimating the global cancer burden due to low levels of physical activity

Rationale. Around 40% of all cancers are thought to be avoidable by modification of lifestyle factors. Obesity has been found to be a risk factor for several cancers and was estimated to have caused around 3.6% of all new cancers which occurred in 2012. Read more

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