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Pharmacology / Toxicology PhD Projects, Programs & Scholarships in Bristol

We have 19 Pharmacology / Toxicology PhD Projects, Programs & Scholarships in Bristol

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Bristol  United Kingdom

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We have 19 Pharmacology / Toxicology PhD Projects, Programs & Scholarships in Bristol

SELF-FUNDING MSc BY RESEARCH PROJECT: Cystic fibrosis: restoring ion transport with small molecules

Cystic fibrosis (CF) is caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR), a unique ATP-binding cassette transporter that functions as an ATP-gated anion channel, playing a pivotal role in salt and water movement across epithelial tissues (1). Read more

Evaluation of novel therapies for human coronary artery bypass graft disease

Brief Rationale. Vascular smooth muscle cell (VSMC) proliferation leads to intimal thickening, which causes reoccurrence of symptoms (restenosis) in 30-50% of coronary artery disease patients receiving saphenous vein grafts [1-2]. Read more

Exploring the similarities between neointimal formation after vascular injury and tumour growth

Rationale. Vascular smooth muscle cell (VSMC) proliferation leads to intimal thickening, which causes reoccurrence of symptoms (restenosis) in 30-50% of coronary artery disease patients receiving saphenous vein grafts and individual receiving stent implantation. Read more

Investigating the role of the regulatory renin-angiotensin system in protecting against synaptic dysfunction in Alzheimer’s disease

Rationale. Mid-life hypertension is a modifiable risk factor for Alzheimer’s disease (AD) and blood pressure lowering drugs, especially those that target the brain renin-angiotensin system (RAS), lowers the incidence of AD, and reduces the conversion of MCI and slows the progression of AD. Read more

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