Our ability to fight infections relies not on the capacity of our professional immune system to defend our body but also on the skills of individual cells to defend themselves. Read more
TRIM21 is the cytosolic E3 ligase and antibody receptor responsible for intracellular antibody immunity. Unlike other ubiquitin ligases, TRIM21 doesn’t have a defined substrate but is directed towards its targets by antibodies. Read more
In this age of increasing antimicrobial resistance, bacterial infections remain a major global health burden. During infection, bacterial pathogens deliver virulence proteins into the host cells. Read more
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