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Biochemistry PhD Projects, Programs & Scholarships in Cambridge

We have 34 Biochemistry PhD Projects, Programs & Scholarships in Cambridge

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Chemical Sciences

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Location

Cambridge  United Kingdom

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We have 34 Biochemistry PhD Projects, Programs & Scholarships in Cambridge

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Interrogating the function of deubiquitylases

Industrial Supervisor. Andy Pearce (MISSION Therapeutics). The Babraham Research Campus (BRC) is pleased to announce that it has been awarded a BBSRC Collaborative Training Partnership (CTP) Award for 15 PhD Studentships (5 per year for 3 years) to start in October 2022. Read more

Exploring the Molecular Architecture of FADD:Caspase-8 Signalling Platforms and how this determines cell fate

 Following exposure to drugs or environmental agents, several large multi-protein signalling platforms play a key role in determining cell death or survival. Caspase-8, a key regulator of cell fate, is recruited/activated within these complexes; for example, the Death-Inducing Signalling Complex (DISC), Necrosome and Ripoptosome. Read more

Nanometer scale mapping as a tool to analyse adverse outcome pathways

Super-resolution fluorescence microscopy has revolutionized the understanding of cellular organization by allowing quantitative analysis of protein assemblies architecture, in situ, at the nanoscale (Sydor et al. Read more

Phase transitions underlying viral replication: understanding the selectivity of viral replication factories through the lens of biomolecular condensates

There is an urgent need for new drugs to combat pathogenic viruses. Most existing antivirals inhibit virus attachment/entry or target key enzymes, and new antiviral targets are needed to develop novel treatments and counter antiviral resistance. Read more

Mapping the conformational signalling landscape of G protein-coupled receptors (GPCRs)

As a research group we are interested in the role that G protein-coupled receptors (GPCRs) play in cellular signalling. We aim at understanding how these membrane embedded receptors function and what external factors influence their behaviour as sensors of the cell. Read more

Structure, regulation and dynamics of small G proteins and their interactions with membranes and effector proteins

Our lab are interested in cell signalling via small G proteins of the Ras superfamily. We use a range of biochemical, biophysical and structural approaches to understand these fascinating proteins, which are involved in multiple cellular processes and are often deregulated in diseases such as cancer. Read more

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