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We have 22 Medicine PhD Projects, Programmes & Scholarships for UK Students in Cambridge
Medicine PhD Projects, Programmes & Scholarships for UK Students in Cambridge
We have 22 Medicine PhD Projects, Programmes & Scholarships for UK Students in Cambridge
Cell biology underlying tuberculosis pathogenesis and drug resistance
TB remains the world’s greatest infectious killer despite a vaccine (BCG) for a century and effective antibiotics for 60 years. TB’s persistence over millennia in the face of major medical advances underscores the ability of Mycobacterium tuberculosis to evade and exploit host defences and antibiotics. Read more
Investigating Novel Transcription of the X Chromosome and its Role in Developmental Disorders of the Human Brain
We hypothesise that annotation of genes and transcripts on the X chromosome is incomplete particularly in the human brain. Read more
Using human organoids to unravel epigenetic mechanisms in health and Inflammatory Bowel Diseases
Project Overview. The intestinal epithelium provides a critical barrier that contributes towards the establishment of a finely tuned homeostasis in the human gut. Read more
Patient outcomes and new therapies in aortic aneurysm using iPSC ‘disease-in-a-dish’ models
Project Overview. We have pioneered the use of induced pluripotent stem cells from patients with genetically mediated aortic aneurysms (such as Marfan and Loeys-Dietz syndromes) to set up ‘disease-in-a-dish’ in vitro models (PMIDs. Read more
Identification of Novel Mechanisms Supporting Axon Survival and Investigation of their Therapeutic Potential
Programmed axon death is a widespread and completely preventable mechanism in injury and disease (Coleman and Hoke, Nat Rev Neurosci, 2020). Read more
Understanding the biology of Foxp3+ CD8+ regulatory T cells and their potential role in multiple sclerosis
CD4+Foxp3+ regulatory T-cells (Tregs) are the most well characterised suppressive cell type in the immune system, with potent roles in suppressing autoimmunity. Read more
IMAGE-D: Integrated Multimodal Analysis for Gaining Enhanced Understanding and Characterization of Dementia
Dementia encompasses various subtypes such as Alzheimer's disease, vascular dementia, and frontotemporal dementia, each affecting different aspect of brain structure and function. Read more
Neurobiology of Consciousness
A significant challenge of contemporary neuroscience is to understand how the neurobiology and function of the human brain give rise to conscious experience. Read more
Mitochondrial Diseases and Immunity
Supervisor. Prof. Rita Horvath . Co-supervisor: Dr. Daniel Lagos . Mitochondria are specialised cell organelles which transform nutrients into energy. Read more
Inflammatory mediators of cerebral autoregulation in acute brain injury
Inflammatory Mediators of Cerebral Autoregulation in Acute Brain Injury” . Supervised by Mr Adel Helmy and Dr Peter Smielewski . Read more
Ultra-High Field (7T and 11.7T) Magnetic Resonance Imaging (MRI) Development
I lead the Ultra-High Field MRI Physics group in Cambridge. We create new methods to studying the human brain and body using Cambridge’s state-of-the-art Siemens Terra 7T MRI scanner and we are preparing new studies for the UK National 11.7T MRI system now being built nearby in Nottingham. Read more
Multimodal Neuroimaging in Atypical Parkinsonian Disorders
To improve our understanding of the progression of neurodegenerative disease, and the mechanisms involved, we need to combine different types of neuroimaging, and integrate it with clinical and genetic data. Read more
Novel Radiotracers and Radiochemical Methods for the Biomedical Technique of Positron Emission Tomography (PET)
With strong alignment to the clinical programmes within the Department of Clinical Neurosciences and other departments in the Clinical School, our programme… Read more
Gaining Control of Intracellular Stages for Amyloidogenesis via High-Resolution Optical Biosensing Approaches coupled to Nanobody-Based Protein Localisation Control
The project focuses on the intracellular stages of amyloidogenesis, aiming to unravel the complex mechanisms contributing to diseases such as Alzheimer's. Read more
Development of PET Radiotracers for Neuroinflammation
Our aim is to develop novel Positron Emission Tomography (PET) radiotracers for imaging the brain. PET is a non-invasive molecular imaging technique which enables visualization and quantification of various biological targets in vivo (e.g., receptor, enzyme). Read more
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