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We have 28 Neuroscience PhD Projects, Programmes & Scholarships for European Students (exc UK) in Cambridge
Neuroscience PhD Projects, Programmes & Scholarships for European Students (exc UK) in Cambridge
We have 28 Neuroscience PhD Projects, Programmes & Scholarships for European Students (exc UK) in Cambridge
Neurobiology of Consciousness
A significant challenge of contemporary neuroscience is to understand how the neurobiology and function of the human brain give rise to conscious experience. Read more
Ultra-High Field (7T and 11.7T) Magnetic Resonance Imaging (MRI) Development
I lead the Ultra-High Field MRI Physics group in Cambridge. We create new methods to studying the human brain and body using Cambridge’s state-of-the-art Siemens Terra 7T MRI scanner and we are preparing new studies for the UK National 11.7T MRI system now being built nearby in Nottingham. Read more
Machine Learning Supported Application of Advanced Neuromonitoring for Individualised Guided Management of Acute Traumatic Brain Injury in Intensive Care
Traumatic brain injury is an extremely complex pathology with a highly dynamic time profile developing over the course of the very first days in a critical care unit. Read more
Comparative connectomics across sexes in Drosophila larvae
The neural circuit wiring diagram varies across sexes. In the adult fly, the gene fruitless has been associated with prominent changes across the nervous system between males and females. Read more
Supra-molecular architecture of neurotransmitter receptor complexes
Chemical synapses are cellular connectors that define the organization and function of neuronal circuits and, as a result, the fundamental ability of the brain to acquire, process and store information. Read more
Circuit basis of learning and action-selection in Drosophila
The overall goal of our research is to discover the circuit implementation of learning and action selection. Since these functions likely emerge from… Read more
Pathological protein assembly in neurodegenerative diseases
Neurodegenerative diseases are one of the greatest health challenges facing our society. This large group of diseases is characterised by the pathological assembly of specific proteins into filaments in the central nervous system. Read more
Connectomic characterization of the zebra finch song system
How do animals store learned behaviours in their neuronal networks and retrieve them when performing those behaviours? It is widely believed that synapses, or connections between neurons, are the memory substrate for learned behaviours. Read more
Investigating Novel Transcription of the X Chromosome and its Role in Developmental Disorders of the Human Brain
We hypothesise that annotation of genes and transcripts on the X chromosome is incomplete particularly in the human brain. Read more
Structure and signalling of AMPA glutamate receptors in synaptic plasticity
Information transfer in the brain occurs at synapses, where memories are stored as a result of synaptic plasticity processes. AMPA-type glutamate-receptors (AMPA-Rs) ion channels, are the main mediators of signal transmission, and centrally contribute to synaptic plasticity. Read more
Cryo-EM studies of amyloids in neurodegenerative diseases
Abnormal filamentous inclusions of the proteins amyloid-beta, tau and alpha-synuclein characterise multiple human neurodegenerative diseases, which are called beta-amyloidoses, tauopathies and synucleinopathies, respectively. Read more
Boosting protein quality control systems to treat neurodegenerative diseases
The deposition of misfolded proteins is a defining feature of many age-dependent human diseases, including the increasingly prevalent neurodegenerative diseases. Read more
Understanding the role of lysosomal TMEM106B in brain ageing and disease
Our group studies mechanisms of brain health, ageing and disease focusing on the lysosomal protein transmembrane protein 106B (TMEM106B) which forms amyloids in the brain in an age-dependent manner. Read more
Identification of Novel Mechanisms Supporting Axon Survival and Investigation of their Therapeutic Potential
Programmed axon death is a widespread and completely preventable mechanism in injury and disease (Coleman and Hoke, Nat Rev Neurosci, 2020). Read more
Understanding the biology of Foxp3+ CD8+ regulatory T cells and their potential role in multiple sclerosis
CD4+Foxp3+ regulatory T-cells (Tregs) are the most well characterised suppressive cell type in the immune system, with potent roles in suppressing autoimmunity. Read more
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