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University of Oxford Cancer Biology PhD Projects, Programmes & Scholarships

We have 15 University of Oxford Cancer Biology PhD Projects, Programmes & Scholarships

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Biological Sciences

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University of Oxford

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We have 15 University of Oxford Cancer Biology PhD Projects, Programmes & Scholarships

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Determining tumour state using DNA methylation

This project is a collaboration between three research groups. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more

Molecular mechanisms of action and basis of resistance to hypomethylating agents in cancer

The student will be supervised by two supervisors. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more

Single Molecule-based Detection of Mutations in Non-clonal cells

This project is a collaboration between two research groups. Prof Skirmantas Kriaucionis research group aims to elucidate the molecular function of DNA modifications in normal cells, leading to the understanding of how defective pathways contribute to the neoplasia. Read more

Why cell position matters in cancer: role of epigenetic factors

Although cancers are highly mutated, it is factors above and beyond those mutations that allow a tumor to form. These factors include epigenetic gene programs embedded within the cell of origin (Baggiolini, et al, Science 2021). Read more
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Ultrastructural insights into avian herpesvirus-host cell interactions

Marek’s disease virus (MDV) is a major avian alphaherpesvirus associated with Marek’s disease (MD) in poultry characterised by rapid-onset T-cell lymphomas, immunosuppression and paralysis causing annual economic losses of around $2 billion worldwide. Read more

Origins of Genotoxic metabolism and the DNA damage response in stem and cancer cells

Our work has shown that metabolism both generalized and intrinsic to blood stem cells unleashes reactive metabolites such as the aldehydes – formaldehyde and acetaldehyde. Read more

Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing

The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more

Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing

The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more

Genome Diversification in Cancer and Adaptive Immunity

Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more

Genome Diversification in Cancer and Adaptive Immunity

Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more

Epigenetic regulation of cholangiocarcinoma growth

Cholangiocarcinoma (CCA) is a rare malignant bile duct tumour with an average incidence of 1/100,000 in the population per year. The overall incidence of CAA includes 15% of primary liver cancers, the second most common type of primary liver cancer. Read more

EPSRC Centre for Doctoral Training in Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research - SABS

Applications are still being accepted. This may change at short notice once all places have been filled. We welcome applications from graduates who wish to make an impact in the field of computational biomedical research. Read more
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