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Cancer / Oncology (cell therapy) PhD Projects, Programs & Scholarships

We have 63 Cancer / Oncology (cell therapy) PhD Projects, Programs & Scholarships

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We have 63 Cancer / Oncology (cell therapy) PhD Projects, Programs & Scholarships

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Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy. Read more

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Tumour metabolic and immune landscape in spatial resolution: using engineered bacterial cancer therapy to enhance anti-tumour T cell responses

Bacterial cancer therapy (BCT) is a promising and versatile therapeutic for solid tumours. Salmonella enterica Typhimurium (STm) is the most well-studied among bacterial vectors due to advantages in ease of genetic modification, metabolic adaptation, and motility. Read more

Unravelling mechanisms of disease progression in Myeloproliferative Neoplasms

The Haematopoietic Stem Cell Biology (HSCB) Laboratory is focused on understanding how the normal haematopoietic stem/progenitor hierarchy is disrupted during the development of myeloid malignancies. Read more

Unravelling mechanisms of disease progression in Myeloproliferative Neoplasms

The Haematopoietic Stem Cell Biology (HSCB) Laboratory is focused on understanding how the normal haematopoietic stem/progenitor hierarchy is disrupted during the development of myeloid malignancies. Read more

Regulation of asymmetric cell division in brain cancer stem cells

Glioblastoma is the most lethal brain cancer in adults. Its poor prognosis is a result of aggressive tumour growth, therapeutic resistance, and tumour heterogeneity at the cellular and genetic level. Read more

MRC DiMeN Doctoral Training Partnership: Elucidating a structural basis for pathogenic mutations in B cell lymphoma

Cancer is a major health problem worldwide and it is believed that 1 in 2 people will develop a form of cancer in their lifetime. Despite recent progress in our understanding of cancer cell biology, current treatments are only effective for some patients. Read more

Cancer therapy endocytosis

This is a project which aims to investigate how tumours and normal tissue internalise drugs such as cancer therapy antibodies in real in vivo models and in patients. Read more

Nanoparticle synthesis and application in magnetic field hyperthermia for cancer therapy

  Research Group: Chemistry and Biosciences
Magnetic field hyperthermia (MFH) is currently undergoing clinical trials for use in humans. The research to date has shown the effectiveness of the approach in cells and animal models and the initial results from human trials are promising. Read more

PhD topic / PhD position: Prioritizing drug combinations in leukemia based on analysis of targetted therapy in vivo

Supervisor: Miroslav Boudny. Consultant: Marek Mraz. Annotation: We are looking for a motivated PhD student that would like to work on the following project funded by the ERC (European Research Council) Starting grant. Read more

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