Cancer Biology (enzyme) PhD Projects, Programmes & Scholarships

We have 11 Cancer Biology (enzyme) PhD Projects, Programmes & Scholarships

Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

University of Bradford Faculty of Life Sciences

Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more

Supervisors: Prof K Pors, Dr V Vangala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy

Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Revealing Reactivity in Cancer-Associated Heme Proteins: Novel Time-Resolved Structural Approaches

University of Leicester Molecular and Cell Biology

Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme involved in the degradation of tryptophan to kynurenine. Cancer cells upregulate IDO1 to escape normal immune responses and, in many cases, a high expression of IDO1 is connected to poor prognosis. Read more

Supervisors: Dr HK Kwon, Dr P A Ash

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

University of Leeds Faculty of Medicine and Health

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Supervisors: Prof M Wilcox, Dr K Davies, Dr A Buckley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology

The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more

Supervisors: Dr C Dominguez, Prof A Fry

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Analysing the role of statins in cardiovascular protection

University of Liverpool Department of Pharmacology and Therapeutics

Drug-induced cardiovascular toxicity is a major problem affecting a number of cancer chemotherapy drugs (Cross et al., 2015). Read more

Supervisors: Dr M Cross, Dr B Wilm, Dr AM Mondru

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Supervisors: Prof R Falconer, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Pharmaceutical process development, optimization and scale-up of plant-based cancer drugs

University of Adelaide School of Chemical Engineering

Project - We are pleased to announce an exciting PhD opportunity within our ground-breaking project dedicated to the optimization of extraction and purification processes of plant-derived molecules, with potential applications in cancer treatment as a collaborative effort with the South Australian immunoGENomics Cancer Institute. Read more

Supervisors: Dr LT Toronjo-Urquiza , Dr AKJ kumorkiewicz-jamro

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers

University of Reading School of Pharmacy

Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier. Read more

Supervisors: Dr F Greco, Prof H Osborn

Year round applications PhD Research Project Self-Funded PhD Students Only

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Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

University of Leeds Faculty of Medicine and Health

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more

Supervisors: Dr M Lorger, Dr R Salmond

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 11 Cancer Biology (enzyme) PhD Projects, Programmes & Scholarships

Cancer Biology (enzyme) PhD Projects, Programmes & Scholarships

We have 11 Cancer Biology (enzyme) PhD Projects, Programmes & Scholarships

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