Cancer Biology (genome) PhD Projects, Programmes & Scholarships

We have 41 Cancer Biology (genome) PhD Projects, Programmes & Scholarships

Cellular mechanisms of equal chromosome segregation and genome stability

University of Southampton School of Biological Sciences

The PhD project will investigate how chromosomes segregate equally in each cell division through epigenetic regulation of the centromere, and how cells respond in stress conditions to maintain genome instability. Read more

Supervisor: Assoc Prof W.Y.K.Y. Yuen

31 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

University of Dundee School of Life Sciences

T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more

Supervisor: Dr T Ly

Year round applications PhD Research Project Self-Funded PhD Students Only

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Why do cancers cells re-express meiotic SYCP1 protein?

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The aim of meiosis is to generate gametes by recombining the chromosomes and reducing the genome from diploid to haploid. However, in mitosis haploid genome and recombination have catastrophic, oncogenic outcomes. Read more

Supervisor: Dr U McClurg

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

University of Leeds Faculty of Medicine and Health

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Supervisors: Prof M Wilcox, Prof A O'Neill, Dr J Freeman, Dr I Moura

Year round applications PhD Research Project Self-Funded PhD Students Only

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Disrupted SUMO signalling in epithelial cancers, implications for genome stability and response to therapy.

University of Leeds Faculty of Biological Sciences

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Dr A Garvin

Year round applications PhD Research Project Self-Funded PhD Students Only

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The analysis of HIF function in DNA repair and genome stability

University of Sheffield School of Biosciences

DNA damage is a factor that underlies many human diseases. Such damage results in mutations, and if such genetic alterations occur in tumour suppressor or proto-oncogenes it can lead to cancer. Read more

Supervisors: Dr F Van Eeden, Prof S El-Khamisy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding L1 ORF1p and Pin1 interaction to exploit it as a therapeutic strategy for liver cancer (ref: SF22/HLS/APP/SHUKLA)

Northumbria University Faculty of Health and Life Sciences

Primary liver cancer, predominantly hepatocellular carcinoma (HCC), is the 4th commonest cause of cancer death globally. Read more

Supervisor: Dr R Shukla

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating how dormant senescent cells can drive drug-resistance following chemotherapy

University of Dundee School of Medicine

Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic determinants of ultra-complex telomere fusion

Cardiff University Cardiff School of Medicine

We are seeking a motivated molecular biologist to study the mechanisms by which telomere dysfunction impacts cancer genomes. Read more

Supervisor: Prof D Baird

3 May 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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The selective action of RAR ligands

University of Birmingham Institute of Cancer and Genomic Sciences

The cells that sustain a cancer and that are largely responsible for metastatic and aggressive disease are termed cancer stem cells. Read more

Supervisors: Dr M Hoogenkamp, Prof G Brown

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia

University of Liverpool Institute of Systems, Molecular and Integrative Biology

This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more

Supervisors: Dr M Papamichos Chronakis, Prof D MacEwan, Dr A Kanhere

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding centrosome assembly in healthy and cancerous tissue with imaging

University of Leicester Molecular and Cell Biology

This is an opportunity for a scientist to join the lab of Dr Robert Mahen in the Department of Molecular & Cell Biology at the University of Leicester. Read more

Supervisor: Dr R Mahen

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying DNA methylation signatures of prostate cancer progression and mortality among patients with clinically confirmed, localised disease at baseline in a large prospective clinical trial

University of Bristol Bristol Medical School

Rationale. Prostate Cancer (PCa) is a leading cause of male mortality, with 336,000 deaths worldwide each year (1). Although most PCa cases are indolent, slow-growing, and tend not to progress, a subset of PCa cases are more aggressive and will progress to metastases, treatment resistance and death. Read more

Supervisors: Dr P Yousefi, Prof R Martin, Dr M Suderman, Dr A Lane, Dr SM Merriel

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

University of Bristol Bristol Medical School

Rationale. Circulating proteins play fundamental roles in biology and disease aetiology, including development of cancer, and are the direct targets of many drugs (1). Read more

Supervisors: Prof R Martin, Dr JY Yarmolinsky, Dr P Haycock

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression and tumorigenesis

Masaryk University Faculty of Medicine

Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. CDK11 is ubiquitously expressed in all tissues and the CDK11 null mouse is lethal at an early stage of development indicating an important role for Cdk11 in the adult as well as during development. Read more

Supervisor: Dr D Blažek

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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We have 41 Cancer Biology (genome) PhD Projects, Programmes & Scholarships

Cancer Biology (genome) PhD Projects, Programmes & Scholarships

We have 41 Cancer Biology (genome) PhD Projects, Programmes & Scholarships

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