Blood/immune cells sustain life through oxygen supply, resistance to infection, and gatekeeping cancer cells. We developed a powerful stem cell culture system that allowed us to recapitulate blood/immune cell development in human organoids. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project has funding attached, subject to eligibility criteria. Applications for the project are welcome from all suitably qualified candidates, but its funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Blood stem cells are used for treating patients whose bone marrow is no longer able to produce healthy stem cells of their own. Diseases - such as blood cancers like leukaemia and lymphoma, severe aplastic anaemia, sickle cell anaemia and thalassaemia - can require a blood stem cell transplant. A transplant comes with risks, and success rates decline with patient age. . Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project has funding attached for UK and EU students, though the amount may depend on your nationality. Non-EU students may still be able to apply for the project provided they can find separate funding. You should check the project and department details for more information.
Our ultimate purpose is to work in service of patients. RCSI was founded by Royal Charter on 11th February 1784, to set and support professional standards for surgical training and practice in Ireland. Read more
Some or all of the PhD opportunities in this programme have funding attached. Applications for this programme are welcome from suitably qualified candidates worldwide. Funding may only be available to a limited set of nationalities and you should read the full programme details for further information.
An Irish PhD usually takes 3-4 years. Traditional doctorates focus primarily on independent research; structured programmes include additional classes and a greater focus on transferable skills. Most students initially register for an MPhil degree before upgrading to the status of PhD candidate and completing their thesis. This will be assessed through an oral viva voce process involving two examiners.
Infection with human papillomavirus (HPV) is associated with ~5% of all human cancers, in particular cervical cancer. Whilst less common, HPV is also associated with the vast majority (~93%) of anal cancers in the UK. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
How can we target E3 ubiquitin ligases for therapeutic benefit?. Work in the Timms laboratory centres around exploiting cutting-edge genetic technologies to study the ubiquitin-proteasome system (UPS). Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This research project has funding attached. It is only available to UK citizens or those who have been resident in the UK for a period of 3 years or more. Some projects, which are funded by charities or by the universities themselves may have more stringent restrictions.
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Haematopoiesis is a complex, finely-tuned process that produces trillions of new blood cells daily. Adult haematopoietic stem cells (HSCs) are responsible for the lifelong maintenance of this system, making it essential to understand their biology. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project has funding attached, subject to eligibility criteria. Applications for the project are welcome from all suitably qualified candidates, but its funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Notch is a developmental signalling receptor with widespread and important roles in metazoan development and also in adult stem cell regulation. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Despite major advances in its early detection, preventive measures and therapeutic options, colorectal cancer is the fourth most commonly diagnosed cancer and the third leading cause of cancer deaths worldwide. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
DNA replication is the fundamental mechanism of genetic inheritance and an essential process for all cellular life. In cancer cells, replication is corrupted and replication forks frequently stall and collapse causing DNA damage and copying errors that drive tumorigenesis. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Carbonic anhydrase (CA) IX is cellular surface protein that in contrast to another isoforms in healthy condition is present mostly in gastrointestinal tract. However, it is highly upregulated in the cancer cells adapting to the extracellular environment while maintaining physiological conditions inside the cancer cell. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project has funding attached, subject to eligibility criteria. Applications for the project are welcome from all suitably qualified candidates, but its funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Application accepted for either MSc by Research or PhD. The urothelium is the self-regenerating epithelium that lines the bladder, where it is highly specialised to function as a urinary barrier. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
How do mutations in chromatin regulators cause disease?. Over half of human cancers contain mutations in chromatin regulators, but our lack of understanding of how these factors exert their function in healthy human cells hampers our ability to design optimal therapeutics. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project has funding attached, subject to eligibility criteria. Applications for the project are welcome from all suitably qualified candidates, but its funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Notch is one of the major highly conserved signalling pathways that regulate cell-cell communication which involves gene regulation mechanisms that control multiple processes during development and adult life, including cell fate specification within progenitors. . Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.