Cancer Biology (human) PhD Projects, Programmes & Scholarships

We have 94 Cancer Biology (human) PhD Projects, Programmes & Scholarships

Transcriptome homeostasis in cellular ageing and cancer

Queen Mary University of London Institute of Dentistry

Project Summary. We have previously established the oncogenic mechanisms of the transcription factor FOXM1 in perturbation of genome stability (1, 2), epigenome (3, 4) and adult progenitor epithelial stem cell proliferation (5). Read more

Supervisor: Dr M T Teh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Why do cancers cells re-express meiotic SYCP1 protein?

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The aim of meiosis is to generate gametes by recombining the chromosomes and reducing the genome from diploid to haploid. However, in mitosis haploid genome and recombination have catastrophic, oncogenic outcomes. Read more

Supervisor: Dr U McClurg

Year round applications PhD Research Project Self-Funded PhD Students Only

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Toxic effects of breast cancer treatment on the heart: using artificial intelligence to predict the potential for heart failure

University of Reading Department of Biomedical Sciences

Project Overview. . Breast cancer is the most common cancer worldwide with ~15% of cases caused by a single gene, HER2. These women are treated with an antibody therapy (e.g. Read more

Supervisors: Prof A Clerk, Prof W Holderbaum, Prof S Nasuto

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells; novel mechanism for drug resistance in leukaemia

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the haematopoietic system become epigenetically reprogrammed and establish immune memory. Read more

Supervisor: Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

University of Reading School of Pharmacy

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more

Supervisor: Prof D Widera

Year round applications PhD Research Project Self-Funded PhD Students Only

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Oncology: Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

University of Leeds Faculty of Medicine and Health

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Supervisors: Dr I Knot, Prof D Jayne

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance

University of Leeds Faculty of Medicine and Health

Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more

Supervisors: Dr G Mavria, Dr S Bell, Dr C Toomes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Complex 3D modelling of the tumour microenvironment for immunotherapy combination screening

University of Leeds Faculty of Medicine and Health

Cancer immunotherapy holds significant promise for the treatment of a range of cancers. Read more

Supervisors: Dr MA Volpato, Dr F Errington-Mais

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells

University of Leeds Faculty of Medicine and Health

Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more

Supervisor: Prof U Klein

Year round applications PhD Research Project Self-Funded PhD Students Only

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Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

University of Leeds Faculty of Medicine and Health

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more

Supervisors: Dr M Lorger, Dr R Salmond

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more

Supervisors: Dr F Errington-Mais, Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

University of Leeds Faculty of Medicine and Health

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

Supervisors: Prof L Houghton, Dr D Peckham

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

University of Leeds Faculty of Medicine and Health

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Supervisors: Prof M Wilcox, Dr K Davies, Dr A Buckley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Why and how do brain tumour cells invade ‘mini-brains’?

University of Leeds Faculty of Medicine and Health

Globally, nearly 189,000 people die each year as a result of brain cancer and around 250,000 people are diagnosed with a malignant brain tumour (umbrella name. Read more

Supervisors: Dr H Wurdak, Dr R Mathew

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Repurposing drugs as new treatments for breast cancer

University of Leeds Faculty of Medicine and Health

Breast cancer (BC) is the most common cancer, with over 1 million new cases diagnosed worldwide each year. For some types of BC, hormonal treatments have been very effective but one particular BC subtype, triple negative breast cancer (TNBC), is highly aggressive and lacks a targeted therapy. Read more

Supervisors: Dr L Matthews, Dr P Meakin

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 94 Cancer Biology (human) PhD Projects, Programmes & Scholarships

Cancer Biology (human) PhD Projects, Programmes & Scholarships

We have 94 Cancer Biology (human) PhD Projects, Programmes & Scholarships

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