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Cancer / Oncology (medicinal) PhD Projects, Programs & Scholarships

We have 13 Cancer / Oncology (medicinal) PhD Projects, Programs & Scholarships

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  Biomolecular Science and Medicinal Chemistry Division PhD project: Proteases in the ubiquitin system – from molecular mechanisms to the development of novel inhibitors
  Dr I Dreveny
Applications accepted all year round

Funding Type

PhD Type

Ubiquitin is a posttranslational modifier that tags substrate proteins for degradation and regulates virtually all known cellular processes.
  Neuropeptide Research - PhD Opportunity at a World Class Institution
  Dr M Muttenthaler, Assoc Prof C Schroeder, Assoc Prof I Vetter
Application Deadline: 4 June 2019

Funding Type

PhD Type

We are seeking talented and highly motivated PhD candidates for the following multidisciplinary project. Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  Structure based design of novel warheads for use in peptide-drug conjugates
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round

Funding Type

PhD Type

Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
  Chemical modulation of cellular redox balance for cancer treatment
  Dr I Romero-Canelon
Applications accepted all year round

Funding Type

PhD Type

Platinum complexes, cisplatin, oxaliplatin and carboplatin, are the most widely used anticancer drugs. However, these DNA-targeting treatments are a low selectivity approach with deleterious consequences and a high incidence of resistance.
  Precious metals in the fight against cancer
  Dr I Romero-Canelon
Applications accepted all year round

Funding Type

PhD Type

Platinum-based complexes, Cisplatin, Oxaliplatin and Carboplatin, are the most widely used chemotherapeutics, nonetheless there is a major unmet clinical need for new treatments that expand the range of treatable cancers and overcome inherent and acquired platinum resistance.
  Activity based proteomic probes for profiling CYP2W1 in cancer tissues
  Research Group: Institute of Cancer Therapeutics
  Dr C Sutton, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

Cytochromes P450 (CYPs) are a superfamily of mixed function oxidases of which CYP1-4 subfamily members are unique in their ability to oxidise drugs.
  Cytochromes P450 in Cancer: Opportunities for Development of Personalised Medicine
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof P Loadman
Applications accepted all year round

Funding Type

PhD Type

The improved understanding of cancer biology provides opportunities for the development of molecular targeted therapies.
  Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Dr S Shnyder
Applications accepted all year round

Funding Type

PhD Type

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs).
  Development of heterocyclic pharmacophores using diversity-oriented synthesis
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof L Patterson
Applications accepted all year round

Funding Type

PhD Type

Diversity-oriented synthesis (DOS) is a modern chemical tool, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression.
  Polysialyltransferases as a target in metastatic cancer
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Dr S Shnyder
Applications accepted all year round

Funding Type

PhD Type

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases.
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