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Cancer / Oncology (proteomic) PhD Projects, Programs & Scholarships

We have 10 Cancer / Oncology (proteomic) PhD Projects, Programs & Scholarships

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  Activity based proteomic probes for profiling CYP2W1 in cancer tissues
  Research Group: Institute of Cancer Therapeutics
  Dr C Sutton, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

Cytochromes P450 (CYPs) are a superfamily of mixed function oxidases of which CYP1-4 subfamily members are unique in their ability to oxidise drugs.
  Elucidation of the role of newly discovered post-translational modification of proteins involved in hypoxia signalling using proteomic analysis and live cell imaging
  Dr V See, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

The hypoxia signalling pathway is required for the adaptation of cells to a low oxygen environment, which cells can experience in various physiological and pathological circumstances related to high altitude, development, wound healing and cancer.
  A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
  Dr C Francavilla, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g.
  Proteomic analyses of adhesion signalling in cancer
  Prof M J Humphries, Dr C Jorgensen
Applications accepted all year round

Funding Type

PhD Type

Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation, and they underpin a metazoan (multicellular) existence.
  Assessment of the predictive value of plasma proteins in oesophageal adenocarcinoma treatment
  Dr AJ Stewart
Application Deadline: 19 July 2019

Funding Type

PhD Type

Applications are invited for a Tenovus Scotland PhD studentship to start in October 2019. The project will be supervised by Dr Alan Stewart, Dr Swati Arya and Dr Peter Caie in the School of Medicine.
  Impact of alternative mRNA splicing on the human proteome
  Dr V Wickramasinghe, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

Alternative splicing of RNA transcripts has emerged as a key mechanism for enabling biological complexity within the human genome.
  The role of isothiocyanates-derived from natural sources in uveal melanoma chemoprevention (ref: SF18/APP/McDermott)
  Prof A McDermott, Prof M Panagiotidis, Dr G Koutsidis
Applications accepted all year round

Funding Type

PhD Type

Uveal melanoma is the most frequent primary intraocular tumor, in Caucasian adults, and one that is very difficult to treat once it becomes metastatic.
  Determining the translational potential of the highly phosphorylated proto-oncogene PBF
  Dr V Smith
Applications accepted all year round

Funding Type

PhD Type

In order to translate the many molecular alterations now detectable in human tumours into effective clinical management we need to fully understand their impact on tumour biology.
  Exploration of 5-fluorouracil resistance mechanisms in colorectal cancer using 5-FU-resistant xenograft models
  Research Group: Institute of Cancer Therapeutics
  Dr S Shnyder, Dr C Sutton
Applications accepted all year round

Funding Type

PhD Type

Despite therapeutic advances, colorectal cancer (CRC) still has a 45% mortality rate, and one of the major problems is the development of acquired resistance to treatment with anticancer drugs.
  LaNts and laminins in breast cancer
  Dr K Hamill
Applications accepted all year round

Funding Type

PhD Type

The laminins are a family of proteins that make up part of specialised regions of extracellular matrix termed basement membranes.
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