Cancer Biology (recombinant) PhD Projects, Programmes & Scholarships

We have 10 Cancer Biology (recombinant) PhD Projects, Programmes & Scholarships

Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more

Supervisors: Dr K Tanaka , Dr R Mahen

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Genomic actions of RAR and VDR ligands

Medical University of Vienna Institute for Pathophysiologie and Allergy

The Doctoral Candidate (DC) will determine whether the combination of RARγ antagonist and VDR agonist is suitable as a differentiation therapy against acute myeloid leukaemia (AML). Read more

Supervisor: Prof E Marcinkowska

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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An Interdisciplinary Approach to Developing of Macrocyclic Inhibitors of the MAPK Pathway

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team: Prof Ali Tavassoli . Project Description. We are seekign an outstanding chemistry student with an interest in chemical biology to work on a project to develop cyclic peptide inhibitors of a protein-protein interaction that is heavily implicated in the development and growth of tumours. . Read more

Supervisor: Prof A Tavassoli

31 August 2024 PhD Research Project Competition Funded PhD Project (European/UK Students Only)

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Self funded MSc by Research or PhD in Biology: The oncogenic mechanism and potential of the emergent retrovirus ALV-K in global poultry

University of York Department of Biology

Lead supervisor: Dr Andrew Mason. The student will be registered with the Department of Biology. Background. Avian Leukosis Viruses (ALV) are oncogenic retroviruses which cause blood cancers in chickens, impacting commercial productivity and animal welfare. Read more

Supervisor: Dr A Mason

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy

Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Role of BTG1 and BTG2 in acute lymphocytic leukaemia and diffuse large B-cell lymphoma

University of Nottingham School of Pharmacy

Acute lymphocytic leukaemia (ALL) and diffuse large B-cell lymphoma (DLBCL) is often associated with small deletions of or point mutations in the highly related BTG1 or BTG2 genes. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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