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Cancer / Oncology (repair) PhD Projects, Programs & Scholarships

We have 16 Cancer / Oncology (repair) PhD Projects, Programs & Scholarships

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  An intelligent scheme to identify novel drug targets through analysing the DNA repairome in drug resistant cancer?
  Research Group: Biomedical Research Group
  Prof C Parris
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  DNA Damage and Repair: Studying DNA damage and repair to understand the causes of cancer and improve its treatment
  Prof P McHugh, Prof J Rehwinkel, Prof A Harris
Application Deadline: 26 July 2019

Funding Type

PhD Type

Our DNA is constantly under threat from damaging agents. If unrepaired this DNA damage can lead to errors during genome duplication, including the mutations that can lead to cancer and other human diseases.
  Defining the ‘molecular signature’ of PARP inhibitor sensitivity in blood cancers
  Dr T Gaymes
Applications accepted all year round

Funding Type

PhD Type

Despite significant advances in the understanding of the biology of blood cancers, identification of the most effective and safe form of treatment continues to present a formidable challenge to clinicians.
  Actin regulation of nuclear mechanics during DNA repair
  Dr C Toseland
Applications accepted all year round

Funding Type

PhD Type

In eukaryotic cells, the nucleus houses the genomic material and transcription machinery that allows the cell to develop and perform its role.
  LaNts in wound repair, stem cell activation and squamous cell carcinoma
  Dr K Hamill
Applications accepted all year round

Funding Type

PhD Type

The Laminin N terminus proteins (LaNts) are a relatively unstudied protein family that are related to netrins and laminins. To date there are only two publications and one preprint about the LaNt proteins in the literature which means there is a massive potential to do novel, ground breaking research in this area.
  Activation of targeted DNA Damage Response as a novel therapy for Ovarian Cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer and accounts for 70% of all ovarian cancer deaths.
  Chromatin and maintenance of genome stability
  Dr A Chambers
Applications accepted all year round

Funding Type

PhD Type

Within eukaryotes, DNA is packaged into chromatin. The basic unit of chromatin is the nucleosome, formed by the wrapping of ~147 bp of DNA around an octamer of histones proteins.
  Understanding the role of HoxA9 in chemotherapy resistance of Acute Myeloid Leukaemia (AML)
  Dr M Esposito
Applications accepted all year round

Funding Type

PhD Type

Acute Myeloid Leukaemia (AML) is a rare but yet deadly form of blood cancer. Genome-wide expression arrays and RNA sequencing have contributed to unravelling the leukaemia signature genes.
  Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
  Dr S Bell, Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Women who have undergone surgery for breast and ovarian cancer often have additional chemotherapy to kill residual cancer cells and prevent recurrence.
  Chromatin remodelling in health and disease: determining the role of ATRX in the maintenance of chromatin and how mutations perturb disparate nuclear nuclear processes and lead to human disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 26 July 2019

Funding Type

PhD Type

It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
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