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We have 12 Cancer Biology (sheffield) PhD Projects, Programmes & Scholarships

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Cancer Biology (sheffield) PhD Projects, Programmes & Scholarships

We have 12 Cancer Biology (sheffield) PhD Projects, Programmes & Scholarships

How does SUMOylation regulate cell survival and death in Heat Shock Response?

Heat shock response (HSR) is a universally existing essential phenomenon for all living organisms to survive sudden increases in environmental temperature that have pronounced damaging effects on important cellular structures and functions (1). Read more

Cancer cells ‘feed’ on extracellular matrix components under starvation conditions: how can they do it?

Background. The tumour microenvironment (TME) has a key role in promoting tumour formation and progression. In breast and pancreatic cancers, this accompanied by the accumulation of extracellular matrix (ECM) in the TME. Read more

Targeting dormant cancer cells in myeloma

Multiple myeloma is the second most common blood cancer and remains essentially incurable. Chemotherapy is effective at reducing tumour and extends survival, but it never fully eradicates disease, so patients face inevitable relapse. Read more

Pharmaceutical process development, optimization and scale-up of plant-based cancer drugs

Project - We are pleased to announce an exciting PhD opportunity within our ground-breaking project dedicated to the optimization of extraction and purification processes of plant-derived molecules, with potential applications in cancer treatment as a collaborative effort with the South Australian immunoGENomics Cancer Institute. Read more

Molecular characterisation of scavenger receptor ligand binding.

Scavenger receptors have been identified as being important in Human disease and normal physiological responses. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously. Read more

The regulation of scavenger receptors in cancer

The expression of some scavenger receptors has been identified as being poor for cancer prognosis. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously in the Human body. Read more

The analysis of HIF function in DNA repair and genome stability

DNA damage is a factor that underlies many human diseases. Such damage results in mutations, and if such genetic alterations occur in tumour suppressor or proto-oncogenes it can lead to cancer. Read more
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