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Cancer / Oncology (unknown) PhD Projects, Programs & Scholarships

We have 14 Cancer / Oncology (unknown) PhD Projects, Programs & Scholarships

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  Egr2 and 3 mediated T cell tolerance in cancer and their impact in immune checkpoint therapy
  Dr S Li
Applications accepted all year round

Funding Type

PhD Type

Tumour infiltrated lymphocytes (TILs) contain tumour reactive T cells and have been used as adoptive cell transfer therapy in patients which can mediate cancer regression.
  Transcriptional evolution of hepatocellular carcinoma in genetically engineered mouse models
  Dr TG Bird
Application Deadline: 3 June 2019

Funding Type

PhD Type

Hepatocellular carcinoma (HCC) is the third most deadly form of cancer globally and has increased dramatically in recent years in the UK.
  Development of targeted therapy for acute myeloid leukaemia with mutations in isocitrate dehysdrogenase
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

Acute Myeloid Leukaemia (AML) is an aggressive disease with poor prognosis and development of novel treatment options is urgently needed.
  Impact of alternative mRNA splicing on the human proteome
  Dr V Wickramasinghe, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

Alternative splicing of RNA transcripts has emerged as a key mechanism for enabling biological complexity within the human genome.
  Polo-like kinase inhibitors for targeted therapy in adrenocortical carcinoma
  Dr C L Ronchi, Dr P Foster
Applications accepted all year round

Funding Type

PhD Type

Adrenocortical carcinoma (ACC) is a rare cancer with a generally poor prognosis and partially unknown pathogenesis.
  Development of heterocyclic pharmacophores using diversity-oriented synthesis
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Prof L Patterson
Applications accepted all year round

Funding Type

PhD Type

Diversity-oriented synthesis (DOS) is a modern chemical tool, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression.
  Development of novel cancer treatments: structural studies of Nectin 4 in complex with bespoke anti-cancer peptides – to start October 2019 - for an MSc by Dissertation (MSD)
  Dr F Prischi, Dr V Bavro
Application Deadline: 1 July 2019

Funding Type

PhD Type

Scientific background. This project targets the current gap in therapeutic approaches targeting Triple Negative Breast Cancer (TNBC) that, unlike other breast cancer subtypes, lacks recommended chemotherapy treatment.
  (MCRC Non-Clinical) Developing ex vivo models for breast cancer - understanding the link between tissue mechanics, genetic instability and cancer initiation
  Dr A P Gilmore, Dr R Clarke, Dr S Howell
Application Deadline: 26 May 2019

Funding Type

PhD Type

Breast cancer is the most common form of cancer in women, with over 54,000 new cases each year in the UK, and over 11,500 of these women die.
  Characterizing the heterogeneity of stem cells in the normal breast and breast tumours
  Dr A Ucar, Prof K R Brennan
Applications accepted all year round

Funding Type

PhD Type

Tissue-restricted stem cells are crucial in supporting the development and maintenance of normal tissues. This is also true for tumours, as only a small population of tumour cells, which are known as cancer stem cells, have the unique stemness features and tumour-initiating capacity.
  CRISPR CAS9 Genome Editing to Study PIP5K1A in Cancer Cells
  Prof D Heery
Applications accepted all year round

Funding Type

PhD Type

Human PIP5K1A is one of a family of kinases that generate the signalling molecule phosphatidylinositol 4,5-bisphosphate (PIP2) in cells.
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