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Cancer Biology (testing) PhD Projects, Programmes & Scholarships

We have 19 Cancer Biology (testing) PhD Projects, Programmes & Scholarships

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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

University of Bristol Bristol Medical School
Rationale. Circulating proteins play fundamental roles in biology and disease aetiology, including development of cancer, and are the direct targets of many drugs (1). Read more
 Supervisors: Prof R Martin, Dr JY Yarmolinsky, Dr P Haycock
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Immune function and exercise in patients undergoing neoadjuvant chemotherapy for breast cancer.

Edinburgh Napier University School of Applied Sciences
Breast cancer is the most common cancer diagnosis in women worldwide. There are on average 55,920 new cases of breast cancer each year in the UK. Read more
 Supervisors: Dr F Brown, Dr I Gallagher, Dr J Turner
 10 June 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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(MRC DTP CASE) Designing Peptide hydrogels as vehicles for targeted and localised in-vivo therapeutics delivery

The University of Manchester Faculty of Biology, Medicine and Health
One of the key engineering challenges in the life-science and biomedical sectors is the design and manufacturing of bespoke hydrogels for 3D cell culture, tissue engineering and cell/drug delivery. Read more
 Supervisors: Prof A Saiani, Dr K Finegan
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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PhD position in plasma safety and effects on human patient samples and DNA-repair mechanisms

Leibniz-Institute for Plasma Science and Technology (INP) ZIK plasmatis
Short overview of PlasmACT. The PlasmACT network brings together 5 beneficiaries and 10 associated partners, located in 5 different countries (Germany, France, Netherlands, Belgium, and Luxembourg). Read more
 Supervisor: Dr LB Böckmann
 30 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences
  Research Group: Medicines Development and Pharmaceutical Sciences
The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more
 Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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New Drugs for Brain Tumours: A Locoregional Implant Brain Tumours

University of Bradford Faculty of Life Sciences
  Research Group: Medicines Development and Pharmaceutical Sciences
Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. Read more
 Supervisors: Dr R Wheelhouse, Prof A Paradkar, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding Hormone Regulation in Skin Cancer Development and Progression

University of York York Biomedical Research Institute
Skin cancers, including melanoma and non-melanoma skin cancers, pose a significant global health burden. While the role of hormones in skin cancer development and progression remains an underexplored area, recent research has suggested potential links between hormonal regulation and skin cancer outcomes. Read more
 Supervisors: Dr M Yamada, Prof T Prow
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Ejecting infection: Understanding how epithelial tissues rid themselves of viral infections by apical extrusion

University of York York Biomedical Research Institute
Background. The epithelial tissues of our bodies use physical barriers and innate defences to fight viral infection. Read more
 Supervisor: Dr S Baker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Improvements of asparaginase-based treatment for Childhood ALL

Cardiff University Cardiff School of Biosciences
Project Description. Most popular current treatments for childhood acute lymphoblastic leukaemia (ALL) in clinic are based on asparaginase (Raja et al 2012). Read more
 Supervisors: Dr O V Gerasimenko, Dr J Gerasimenko
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases

University of Leicester Molecular and Cell Biology
Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more
 Supervisor: Prof S Macip
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identifying DNA methylation signatures of prostate cancer progression and mortality among patients with clinically confirmed, localised disease at baseline in a large prospective clinical trial

University of Bristol Bristol Medical School
Rationale. Prostate Cancer (PCa) is a leading cause of male mortality, with 336,000 deaths worldwide each year (1). Although most PCa cases are indolent, slow-growing, and tend not to progress, a subset of PCa cases are more aggressive and will progress to metastases, treatment resistance and death. Read more
 Supervisors: Dr P Yousefi, Prof R Martin, Dr M Suderman, Dr A Lane, Dr SM Merriel
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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ROLE OF FOXO1 TRANSCRIPTION FACTOR IN B-CELL MALIGNANCIES

Masaryk University Faculty of Medicine
The project is focused on FoxO1 transcription factor and its role in the pathophysiology of chronic lymphocytic leukemia (CLL). Although the therapy of CLL has made several remarkable improvements, the disease still remains incurable. Read more
 Supervisor: Assoc Prof Marek Mraz
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Discovery of Novel Cancer Immunotherapeutic Agents

Cardiff University Cardiff School of Pharmacy and Pharmaceutical Sciences
Summary. Although cancer therapeutics, mainly chemotherapy and radiotherapy, have been extremely useful in the treatment of cancer, this disease is still associated with high morbidity and mortality. Read more
 Supervisor: Dr Y Mehellou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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