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We have 5 Cancer Biology (yeast) PhD Projects, Programmes & Scholarships

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Cancer Biology (yeast) PhD Projects, Programmes & Scholarships

We have 5 Cancer Biology (yeast) PhD Projects, Programmes & Scholarships

Obtaining insights into how a signalling hub protein Ras activates multiple effectors

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more

Assessment of phototherapy with model organism Saccharomyces cerevisiae

Project Overview.  . Saccharomyces cerevisiae is extensively used as model organism and is well understood from a sequencing perspective so up-regulation or down-regulation of gene expression is tractable. Read more

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Cellular mechanisms of equal chromosome segregation and genome stability

The PhD project will investigate how chromosomes segregate equally in each cell division through epigenetic regulation of the centromere, and how cells respond in stress conditions to maintain genome instability. Read more

Understanding gene regulation by HDAC1 complexes in development and cancer

Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
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