Imperial College London Featured PhD Programmes
University of Southampton Featured PhD Programmes
University of Reading Featured PhD Programmes
"cell" AND "culture"×
10 miles

Cancer / Oncology (cell culture) PhD Projects, Programs & Scholarships

We have 86 Cancer / Oncology (cell culture) PhD Projects, Programs & Scholarships

  • "cell" AND "culture" ×
  • Cancer / Oncology×
  • clear all
Order by 
Showing 1 to 30 of 86
  Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
  Dr E Valleley, Dr L Coletta
Applications accepted all year round

Funding Type

PhD Type

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (such as DNA methyltransferase inhibitors), as a potential combination therapy for colorectal cancer (CRC).
  Microtubule motors in cell migration and integrin trafficking
  Prof V Allan, Prof P Woodman, Dr P Caswell
Applications accepted all year round

Funding Type

PhD Type

Cell migration is vital for the development and health of multicellular organisms. However, enhanced cell migration is also a hallmark of cancer cells, and contributes greatly to metastasis.
  Predicting the development of oral cancer
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Human head and neck cancer is a devastating disease with poor survival rates.
  ’Follow my leader’: in vitro studies of oral cancer cell motility
  Dr S Whawell, Dr H Colley
Applications accepted all year round

Funding Type

PhD Type

Oral cancer cell invasion is a crucial step in the progression of the disease and is mediated by interactions with the extra cellular matrix and factors released by the tumour cells as well as cells that occupy the tumour microenvironment (stroma).
  The functional characterization of the tumour suppressor gene CSMD1 in breast cancer
  Dr S Bell
Applications accepted all year round

Funding Type

PhD Type

CUB and Sushi multiple domains protein 1 (CSMD1) maps to 8p23, a region deleted in many cancers including breast cancer. Our previous work has established that CSMD1 is an independent prognostic marker in ductal breast cancer, with reduced expression associated with high tumour grade and poor survival1.
  Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells.
  Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
  Dr J Bruce, Prof K Williams, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy.
  Diagnostic and therapeutic biomarkers in lung cancer
  Dr D CL Lam
Applications accepted all year round

Funding Type

PhD Type

The aim of my research laboratory is to develop and implement new ways to improve the prevention, early detection, diagnosis and treatment of lung cancer through multi-disciplinary research that translates results between the laboratory and the clinic.
  Identification of key determinants affecting the quality of human Cancer specific cytotoxic T cells
  Prof T Dong
Application Deadline: 24 July 2020

Funding Type

PhD Type

The main objective of my group’s research is to focus on the functional aspects of the antigen specific T cells and study the factors affecting Cytotoxic T cells in controlling cancer development.
  Identification of key determinants affecting the quality of human Cancer specific cytotoxic T cells
  Prof T Dong
Application Deadline: 24 July 2020

Funding Type

PhD Type

The main objective of my group’s research is to focus on the functional aspects of the antigen specific T cells and study the factors affecting Cytotoxic T cells in controlling cancer development.
  Investigating the role of the protease ADAMTS5 in ovarian cancer
  Dr E Rainero
Applications accepted all year round

Funding Type

PhD Type

Ovarian cancer is the most lethal gynaecological malignancy. Mostly because of late stage diagnosis, the 5-year survival rate is.
  Accelerating our ability to understand and target complexity and heterogeneity in cancer through automated imaging of 3D cancer models including patient derived organoids
  Dr C Dunsby, Prof P French
Application Deadline: 31 August 2020

Funding Type

PhD Type

Drug resistance is a major challenge for cancer therapy, arising from heterogeneous cellular behaviours within tumours, where initially identical clonal cells can mutate and adapt to diverse microenvironments.
  PhD student (m/f/d): Personalizing the diagnosis, prognosis and treatment options for patients with these hematologic neoplasias
  Dr B Chapuy
Application Deadline: 30 April 2020

Funding Type

PhD Type

The Clinic of Hematology and Oncology, the group of Professor Dr. med. Björn Chapuy offers a position for. PhD student (m/f/d). limited (3 years), full time position, salary according to TV-L.
  Redeploying Rucaparib: Can PARP inhibitors alter deregulated cellular bioenergetics and overcome apoptosis resistance in cancer? (SF20/APP/WALDEN)
  Dr H Walden
Applications accepted all year round

Funding Type

PhD Type

Poly(ADP-ribose) polymerase inhibitors (PARPi) have received huge attention in oncology over recent years. They are FDA approved for use in BRCA1/2 defective breast and ovarian cancers with absent or dysfunctional homologous recombination repair function.
  Characterization and functional analysis of a novel cancer-associated gene
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

This opportunity will remain open until the position has been filled. In order to identify new candidate cancer-related genes, our lab developed a bioinformatics “guilt-by-association” method to identify and rank genes that are co-expressed with known cancer-related genes.
  Understanding the gene regulatory landscape of embryonic stem cells and cancer cells
  Prof A Sharrocks, Prof M Rattray
Applications accepted all year round

Funding Type

PhD Type

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity.
  Induced pluripotent stem-cell (iPSC) reprogramming in bone and blood cancers (Ref:SF20/APP/PAL)
  Dr D Pal
Applications accepted all year round

Funding Type

PhD Type

iPSC (somatic cells reprogrammed to an embryonic-stem-cell-like state) are not only a means of patient relevant disease modelling, but de-differentiation of terminal cells to their primitive precursors often reveal aberrations in tissue development.
  Characterisation of the role of the adhesion protein tensin 3 in breast cancer progression
  Dr E Rainero
Applications accepted all year round

Funding Type

PhD Type

Breast cancer arises from the transformation of mammary epithelial cells. In the healthy tissue, these grow as a single monolayer of cells delimiting an internal hollow lumen 2.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy
  Prof K Gaston, Dr P-S Jayaraman
Applications accepted all year round

Funding Type

PhD Type

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies.
  Investigating the requirements of pro-inflammatory signaling in skin and head & neck Squamous Cell Carcinomas
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Squamous cell carcinomas (SCC) are amongst the most common cancer types afflicting man. SCCs most frequently arise from stratified squamous epithelia such as the epidermis or the mucosae of the head and neck.
  Preparing the acid bath: how epidermal growth factor receptor (EGFR) controls its own down-regulation
  Prof P Woodman, Dr C Francavilla
Applications accepted all year round

Funding Type

PhD Type

Signalling by cell surface receptors determines nearly every aspect of the cell’s response to its environment. Endosomes are hubs for regulating these signalling pathways.
  Precision Medicine DTP - Proteomic analysis of FAK function in human pancreatic cancer
  Research Group: Centre for Inflammation Research
  Dr A Serrels, Dr A Byron, Dr A von Kriegsheim
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. In the United Kingdom, the 5-year survival rate for patients with pancreatic ductal adenocarcinoma (PDAC) is just 3% (Cancer Research UK statistics), and as a result pancreatic cancer is the 4th most common cause of cancer death in the UK and US.
  Homeostatic mechanisms in human urothelium: balancing of tissue regeneration and differentiation with implications for regenerative medicine and cancer
  Prof J Southgate
Application Deadline: 30 June 2020

Funding Type

PhD Type

The urothelium is the self-regenerating epithelium that lines the bladder, where it is highly specialised to function as a urinary barrier.
  The role of the breast microenvironment in suppressing early cancer invasion
  Assoc Prof B Parker, Dr D Zanker
Applications accepted all year round

Funding Type

PhD Type

Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer, whereby the tumour cells remain restrained by myoepithelial cells that surround breast ducts.
  Exploiting tumour-promoting paracrine signals in solid cancers to turbocharge genetically redirected T cells
  Dr A Hurlstone, Prof R Edmondson
Applications accepted all year round

Funding Type

PhD Type

Adoptive cell therapy (ACT) using tumour infiltrating lymphocytes (TILs) or genetically redirected T cells are some of the most promising approaches to emerge recently for the treatment of metastatic disease.
  Carbon Nanotubes Mediated Drug Delivery in 3D cancer models
  Dr H Ali-Boucetta
Applications accepted all year round

Funding Type

PhD Type

Current treatment with anticancer drugs suffers from the drawbacks of systemic toxicity, drug resistance and limited cellular entry.
  Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
  Dr S Bell, Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Women who have undergone surgery for breast and ovarian cancer often have additional chemotherapy to kill residual cancer cells and prevent recurrence.
  Fueling chemotherapy resistance in triple-negative breast cancer
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

Triple-negative breast cancer (TNBC) is a molecularly heterogeneous group of diseases defined by the lack of estrogen receptor (ER), progesterone receptor (PR) and absence of human epidermal growth factor receptor-2 (HER2) amplification.
  Understanding the mechanisms of neuroendocrine tumour response to radionuclide therapy
  Prof R Hicks, Assoc Prof C Cullinane
Applications accepted all year round

Funding Type

PhD Type

Neuroendocrine tumours (NET) represent a heterogeneous group of tumours that arise in specialized cells found throughout the body.
Show 10 15 30 per page


FindAPhD. Copyright 2005-2020
All rights reserved.