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Cancer / Oncology (infection biology) PhD Projects, Programs & Scholarships

We have 34 Cancer / Oncology (infection biology) PhD Projects, Programs & Scholarships

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  Nucleic Acid Sensing During Virus Infection – Innate Immunity
  Dr J Rehwinkel
Application Deadline: 24 July 2020

Funding Type

PhD Type

Virus infection is a constant threat to the cells of all living organisms. To counter this threat, cellular receptors detect virus presence and activate potent antiviral immune responses.
  Nucleic Acid Sensing During Virus Infection – Innate Immunity
  Dr J Rehwinkel
Application Deadline: 24 July 2020

Funding Type

PhD Type

Virus infection is a constant threat to the cells of all living organisms. To counter this threat, cellular receptors detect virus presence and activate potent antiviral immune responses.
  Understanding the role of DRAM in infection and autophagy-related disease
  Dr J King, Dr P Elks
Applications accepted all year round

Funding Type

PhD Type

Intracellular degradation by lysosomes is important in a wide range of diseases. The capture and degradation of cytoplasmic components by autophagy allows tumour cells to survive starvation and neurons to remove the protein aggregates associated with neurodegeneration.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  PhD Positions in Cancer Research

Funding Type

PhD Type

Are you looking for excellent research opportunities for your PhD studies at the forefront of cancer research? The German Cancer Research Center (DKFZ)…
  Defining the immune cells which best fight cancer
  Prof D Davis
Application Deadline: 4 March 2020

Funding Type

PhD Type

Arguably, immune therapies for cancer are at a tipping point. The success of therapies for some patients with some types of cancer has made it clear that immunotherapies can work.
  MRC DTP 4 Year PhD Programme: Revealing dynamic and elusive early-mitotic events using state-of-the-art live-cell light sheet imaging
  Dr T Tanaka, Dr M MacDonald
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Uncovering molecular details of regulation of the mRNA capping enzymes in gene expression
  Dr A Pisliakov, Prof V Cowling
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Baculovirus P10 and microtubules; the role of P10 in virus-induced nuclear lysis with possible applications for novel anti-cancer therapies
  Prof L A King, Dr V Bolanos-Garcia
Application Deadline: 20 March 2020

Funding Type

PhD Type

Oxford Brookes University. Faculty of Health and Life Sciences,. Department of Biological and Medical Sciences. 3.5 year, full-time PhD iCASE studentship.
  Regulation of apoptosis-induced compensatory cell proliferation and its implications for cancer and tissue regeneration
  Dr Y Fan
Applications accepted all year round

Funding Type

PhD Type

In multi-cellular organisms, coordinated cell death (e.g. apoptosis) and cell replacement is critical for tissue recovery in response to stress or damage.
  Clinical and molecular correlates of response to first line treatment in oral lichen planus
  Dr K Hijazi, Prof J Gibson
Application Deadline: 13 March 2020

Funding Type

PhD Type

Oral lichen planus is a chronic disease of the lining of the mouth that causes pain and increases the risk of oral cancer. The negative impact of oral lichen planus on quality of life has been proven.
  Predicting the development of oral cancer
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Human head and neck cancer is a devastating disease with poor survival rates.
  Stress regulation of protein translation: role in cancer and neurodegeneration
  Dr A J Whitmarsh, Prof M Ashe
Applications accepted all year round

Funding Type

PhD Type

Cells are subjected to a range of stresses that include physical injury, changes in oxygen levels or temperature, nutrient deprivation, radiation and infection.
  Regulation of host cell DNA damage response pathways by adenovirus
  Dr A S Turnell, Dr C McCabe
Applications accepted all year round

Funding Type

PhD Type

Human adenoviruses are small non-enveloped viruses with a linear, double-stranded DNA genome. Adenovirus has long served as a faithful model for dissecting the molecular basis of key cellular signalling pathways that regulate fundamental biological processes such as cell growth, cell differentiation and cell death.
  MRC DTP 4 Year PhD Programme: Investigating the tumour suppressor function of chromatin remodelling enzymes
  Prof T A Owen-hughes, Dr G Schweikert
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Molecular simulation study of the Nrf2-Keap1 pathway, the master regulator of cellular redox homeostasis
  Dr A Pisliakov, Prof A Dinkova-Kostova
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Proteo-Genomic Analysis for Precision Oncology
  Prof A I Lamond, Prof R Petty
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Developing new antibody-based therapeutics for neuroblastoma
  Prof A Sala
Applications accepted all year round

Funding Type

PhD Type

Metastatic neuroblastoma is a cancer of the nervous system that kills the majority of the affected children. Although there have been tremendous advances in the understanding of the molecular causes of the disease, patients are still treated with highly toxic mixtures of chemicals and radiation.
  Telomere length elongation following treatment with chemotherapeutic drugs. Aim: To investigate the mechanisms which leads to telomere length elongation after treatment with tricostatin A and azacytidine.
  Dr T Roberts
Applications accepted all year round

Funding Type

PhD Type

Telomeres are specialised structures, which are present at the ends of chromosomes and serve to protect the chromosome from degradation during cell division.
  Development and evaluation of small Inhibitors of HUWE1 for the treatment of Multiple Myeloma
  Research Group: Centre for Cancer Research and Cell Biology
  Dr L Crawford, Dr R Williams
Application Deadline: 24 February 2020

Funding Type

PhD Type

HUWE1 is a large HECT-domain E3 ligase that is involved in the regulation of key proteins such as p53, MYC and MCL-1. We have identified elevated expression of HUWE1 in Multiple Myeloma (MM) and demonstrate that knockdown of this ligase leads to growth arrest of MM cell lines both in vitro and in vivo.
  Dissecting the mechanisms of antibiotic resistance in Clostridium difficile
  Dr R Fagan
Applications accepted all year round

Funding Type

PhD Type

Antibiotic resistance in pathogenic bacteria is one of the greatest health challenges facing humanity today.
  Exploiting tumour-promoting paracrine signals in solid cancers to turbocharge genetically redirected T cells
  Dr A Hurlstone, Prof R Edmondson
Applications accepted all year round

Funding Type

PhD Type

Adoptive cell therapy (ACT) using tumour infiltrating lymphocytes (TILs) or genetically redirected T cells are some of the most promising approaches to emerge recently for the treatment of metastatic disease.
  Virus pathogenesis: interplay between the unfolded protein response and innate immunity.
  Dr S-W Chan, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

The unfolded protein response (UPR) is a cellular homeostatic response in restoring endoplasmic reticulum balance upon stress conditions e.g.
  Comparative studies of wound and cancer inflammation in plants and animals
  Prof P B Martin
Applications accepted all year round

Funding Type

PhD Type

All organisms need to be able to repair wounds. A key aspect of this is combating the potential for infection when barrier layers are breached by tissue damage.
  Platelet-cell interactions: Platelets beyond thrombosis and haemostasis
  Dr A Pollitt
Applications accepted all year round

Funding Type

PhD Type

"Platelets play a key role in the prevention of bleeding following blood vessel damage.
  Investigating the mechanism of action of dual antiangiogenic/ antineoplastic drugs using organotypic co-culture of fibroblasts and endothelial cells
  Research Group: Institute of Cancer Therapeutics
  Dr J Elies Gomez, Dr K Pors
Applications accepted all year round

Funding Type

PhD Type

An important feature of many types of cancer is the ability to develop abnormal angiogenesis (blood vessel formation); this allows cancer cells to gain access to nutrients and favours metastasis.
  Investigating the impact of particle manufacturing process on nanomedicine biological fate
  Dr Z Rattray, Prof Y Perrie
Application Deadline: 31 March 2020

Funding Type

PhD Type

A new drug candidate faces multiple challenges during its development, and in oncology drug development, a key challenge is achieving the balance between efficacy and off-target toxicity.
  Long-acting drug delivery from intravaginal rings for treatment of cervical intraepithelial neoplasia
  Prof K Malcolm, Dr P Boyd
Applications accepted all year round

Funding Type

PhD Type

Building on our world-renowned expertise in vaginal drug delivery, the aim of this project is to develop a long-acting vaginal ring device for treatment of cervical intraepithelial neoplasia.
  Bacterial-derived magnetosomes as nanocarriers for cancer-killing oncolytic viruses.
  Dr M Muthana, Dr F Howard
Applications accepted all year round

Funding Type

PhD Type

Dysfunctional cellular processes that are the markers of neoplasms provide the ideal environment for viral infection including sustained proliferation and resistance to cell death.
  Egr2 and 3 mediated T cell tolerance in cancer and their impact in immune checkpoint therapy
  Dr S Li
Applications accepted all year round

Funding Type

PhD Type

Tumour infiltrated lymphocytes (TILs) contain tumour reactive T cells and have been used as adoptive cell transfer therapy in patients which can mediate cancer regression.
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