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Cancer / Oncology (information studies) PhD Projects, Programs & Scholarships

We have 95 Cancer / Oncology (information studies) PhD Projects, Programs & Scholarships

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  Inhibition of PRMT5 as a cancer therapy
  Dr K. Sheppard
Applications accepted all year round

Funding Type

PhD Type

Targeted therapy has had profound impact on outcomes for cancer patients.
  How does amino acid metabolism affect tumour growth?
  Dr L. Cheng
Applications accepted all year round

Funding Type

PhD Type

The effect of diet on tumour growth is hotly debated but poorly characterized. Due to the heterogeneous nature of the tumours, dietary studies in patients with varied genetic background often led to inconclusive outcome.
  Metabolic rewiring in liver cancer: Role of oxidative stress and the Nrf2 pathway
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Many of the major risks factors for developing liver cancer such as alcohol, obesity, smoking and toxin exposure share in common a role for oxidative stress.
  Predicting the development of oral cancer
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Human head and neck cancer is a devastating disease with poor survival rates.
  RNA Methylation in normal and malignant blood development
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

As is the case with DNA and histones, RNA can also be modified and indeed more than 100 chemical groups that decorate all four canonical RNA nucleotides have been described.
  Watching the Hippo pathway in real time in growing organs
  Dr K. Harvey
Applications accepted all year round

Funding Type

PhD Type

A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have drawn conclusions about gene function using indirect techniques that only allow us to infer what a gene normally does, without actually watching it work.
  A PhD applying machine learning techniques to Next Generation Sequencing Big Data to improve Prostate Cancer patient outcome. (BrewerD-CooperCU19SF)
  Dr D Brewer, Prof C Cooper
Application Deadline: 31 May 2020

Funding Type

PhD Type

Prostate cancer (PCa) is the second most common cancer in men worldwide and an estimated 307,000 men annually die from PCa worldwide.
  Normal and Leukaemic Blood Stem/Progenitor Cell Biology
  Prof P Vyas, Prof A Mead
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory studies the mechanisms regulating normal blood stem and progenitor cell differentiation and how these are perturbed in blood cancers such as Acute Myeloid Leukaemia (AML) and Myelodysplastic Syndromes (MDS).
  Normal and Leukaemic Blood Stem/Progenitor Cell Biology
  Prof P Vyas, Prof A Mead
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory studies the mechanisms regulating normal blood stem and progenitor cell differentiation and how these are perturbed in blood cancers such as Acute Myeloid Leukaemia (AML) and Myelodysplastic Syndromes (MDS).
  Patient experience of the Mesothelioma Stratified Therapy Trial (MiST): a qualitative study
  Prof A Tod, Dr B Taylor
Applications accepted all year round

Funding Type

PhD Type

This PhD provides a unique opportunity for a student to conduct a qualitative patient experience health services research study within a complex stratified clinical trial for people with malignant mesothelioma (MM), the Mesothelioma Stratified Therapy Trial (MiST).
  Cellular cross-talk at the perivascular niche and the blood brain barrier
  Prof B Hogan
Applications accepted all year round

Funding Type

PhD Type

Much research on vasculature has focussed on the endothelial cells that line functional vessels, however the milieu of cells that surround vessels (mural cells) play important and under-appreciated roles in homeostasis and disease.
  Fueling chemotherapy resistance in triple-negative breast cancer
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

Triple-negative breast cancer (TNBC) is a molecularly heterogeneous group of diseases defined by the lack of estrogen receptor (ER), progesterone receptor (PR) and absence of human epidermal growth factor receptor-2 (HER2) amplification.
  Testing the function of immune suppressive cytokines and cells in bone metastasis
  Assoc Prof B Parker
Applications accepted all year round

Funding Type

PhD Type

Bone metastasis is a common occurrence in breast and prostate cancer that leads to patient morbidity and, in many cases, mortality.
  The Hippo pathway and Yap1 in vascular growth control in development and disease
  Prof B Hogan, Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Lymphatic vessels play roles in the drainage of tissue fluid, trafficking of immune cells and the metastatic spread of cancer.
  Understanding the mechanisms of neuroendocrine tumour response to radionuclide therapy
  Prof R Hicks, Assoc Prof C Cullinane
Applications accepted all year round

Funding Type

PhD Type

Neuroendocrine tumours (NET) represent a heterogeneous group of tumours that arise in specialized cells found throughout the body.
  Micro-environmental Interactions And Non-Coding RNAs In The Biology Of B Cell Leukemia
  Prof M Mráz
Application Deadline: 20 February 2020

Funding Type

PhD Type

We are looking for motivated PhD students for a project funded by the prestigious ERC (European Research Council) Grant (laboratory of Assoc.
  Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
  Dr J Bruce, Prof K Williams, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy.
  Comparative studies of wound and cancer inflammation in plants and animals
  Prof P B Martin
Applications accepted all year round

Funding Type

PhD Type

All organisms need to be able to repair wounds. A key aspect of this is combating the potential for infection when barrier layers are breached by tissue damage.
  Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas
  Research Group: School of Molecular and Cellular Biology
  Dr J Boyes
Application Deadline: 1 April 2020

Funding Type

PhD Type

V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas.
  Characterisation of in vitro models of human salivary glands and their use in functional studies
  Dr L Bingle, Prof C Bingle
Applications accepted all year round

Funding Type

PhD Type

Saliva is produced by three pairs of major salivary glands and multiple minor glands in the lips, associated with the tongue and also with the palate.
  Characterizing the heterogeneity of stem cells in the normal breast and breast tumours
  Dr A Ucar, Prof K R Brennan
Applications accepted all year round

Funding Type

PhD Type

Tissue-restricted stem cells are crucial in supporting the development and maintenance of normal tissues. This is also true for tumours, as only a small population of tumour cells, which are known as cancer stem cells, have the unique stemness features and tumour-initiating capacity.
  Evolution Education Trust PhD project: Quantitative Morphometry in the Evolution of Metastatic Cancer
  Dr J Sero, Prof M A Wills
Application Deadline: 5 February 2020

Funding Type

PhD Type

The University of Bath is inviting applications for this PhD opportunity based at the Milner Centre for Evolution, a unique, cross-faculty research centre bridging biology, health and education.
  Splicing control in tumour angiogenesis. Self funded Medical Studies PhD
  Dr S Oltean
Application Deadline: 27 January 2020

Funding Type

PhD Type

Lead supervisor. Dr Seb Oltean, College of Medicine and Health, University of Exeter. Project description. Abnormal angiogenesis is one of the hallmarks of cancer; tumours need to grow new vessels to be able to survive and spread in the organism.
  Development of new anti-obese strategies by conversion of white fat to brown fat
  Prof A Xu
Applications accepted all year round

Funding Type

PhD Type

In contrast to white adipose tissue (WAT) that stores energy, brown adipose tissue (BAT) is specialized for energy dissipation and considered as a potential weapon to combat obesity by uncoupling mitochondrial respiratory chain and ATP synthesis.
  A multiple modality approach for targeting treatment-resistant ovarian cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer (OvCa) deaths and its five-year survival rate is 43%.
  Analytic methods for detecting and making sense of somatic genomic rearrangements
  Prof A Papenfuss
Applications accepted all year round

Funding Type

PhD Type

Bioinformatics is the application of mathematics, statistics and computational methods to the analysis of molecular biology data.
  Clinical cancer bioinformatics: developing new bioinformatics methods for improved analysis of cancer gene hybridisation capture panels
  Prof A Papenfuss
Applications accepted all year round

Funding Type

PhD Type

Bioinformatics is the application of mathematics, statistics and computational methods to the analysis of molecular biology data.
  Computational simulation of tumour formation and progression
  Dr D. Goode
Applications accepted all year round

Funding Type

PhD Type

Tumours comprise a complex mix of related but distinct cellular subpopulations that both compete and complement one another. These dynamics strongly influence how and when a tumour forms as well as its response to therapy, however there are hard to observe directly.
  Fishing for metabolic clues: Role of the Hippo/Yap pathway in reprogramming metabolism in liver cancer
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

The Hippo/Yap pathway is an evolutionarily conserved cascade that plays a fundamental role in governing organ size control, stem cell homeostasis and cancer.
  Genomic determinants of long-term survival in ovarian cancer
  Research Group: Cancer Genetics & Genomics Laboratory
  Prof D. Bowtell, Dr D Garsed
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer is an aggressive disease in which only ~30% of women survive 5 years or more. Despite a poor prognosis, a subset of patients are highly responsive to chemotherapy, and some become long-term survivors (>10 years survival).
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