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Cancer / Oncology (php) PhD Projects, Programs & Scholarships

We have 19 Cancer / Oncology (php) PhD Projects, Programs & Scholarships

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  Molecular insights into a novel mammalian oxygen-sensing pathway (Ph.D in Biochemistry/Chemical Biology)
  Dr M White, Prof R Payne, Prof J Mackay
Applications accepted all year round

Funding Type

PhD Type

Outstanding candidates with a background in biochemistry, molecular biology, organic chemistry or similar are invited to apply for a fully funded Ph.D scholarship…
  Non-invasive Mapping of Oxygen Extraction Fraction in Patients with Breast Cancer: Development of Novel Multi-Parametric Relaxometry Magnetic Resonance Imaging (MRI) Methods
  Dr J He, Dr Y Masannat, Prof D Lurie
Applications accepted all year round

Funding Type

PhD Type

This project aims to translate, optimise and extend quantitative oxygen extraction fraction mapping based on oxygen enriched air inspiration and magnetic resonance (MR) relaxometric imaging for human application.
  Understanding the health behaviour behind GP help-seeking with potential cancer symptoms.
  Prof P Murchie, Dr D Powell, Dr R Vieira
Applications accepted all year round

Funding Type

PhD Type

1. Background to the project.
  In Silico design and chemoenzymatic synthesis of bioactive cyclic and stapled peptides
  Dr W Houssen, Dr S Dall'Angelo, Dr G S Bewick
Application Deadline: 24 January 2020

Funding Type

PhD Type

Cyclic and modified cyclic peptides are very appealing scaffolds especially as therapeutics with several examples reach the clinic e.g.
  Precision Medicine DTP - Analyzing network formation during brain tumour initiation
  Dr D Sieger, Prof P Uhlén
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. High grade brain tumours (HGBTs) represent a complex and devastating disease and are posing an unmet clinical need. These tumours resist multi-modal therapies and survival times are only 15 months on average.
  Precision Medicine DTP - Comprehensive study of miRNAs biogenesis in human cancer
  Dr G Michlewski, Dr C Kutter
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. MicroRNAs (miRNAs) are short non-coding RNAs ~22 nt in length that function as important regulators of gene expression1.
  Precision Medicine DTP – Development of clinically relevant models of undifferentiated pleomorphic sarcoma using a genetic screening approach
  Research Group: Edinburgh Cancer Research Centre
  Prof V Brunton, Dr L Boulter, Dr M Taylor, Prof D M Salter
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Sarcomas are relatively uncommon cancers thought to arise from pluripotent mesenchymal stem cells. Undifferentiated pleomorphic soft tissue sarcoma (UPS), though one of the commonest sarcoma subtypes encountered, exemplify the limitations of historical progress in sarcoma therapy.
  Precision Medicine DTP – Investigating the metabolic alterations that initiate pre-neoplastic development in zebrafish and in humans
  Research Group: Centre for Inflammation Research
  Dr Y Feng, Dr K Burgess, Dr R Burchmore, Dr G Ho
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. “Warburg metabolism” is characterised by an increased uptake of glucose and its conversion to lactate by glycolysis under normoxia.
  Precision Medicine DTP - Proteomic analysis of FAK function in human pancreatic cancer
  Research Group: Centre for Inflammation Research
  Dr A Serrels, Dr A Byron, Dr A von Kriegsheim
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. In the United Kingdom, the 5-year survival rate for patients with pancreatic ductal adenocarcinoma (PDAC) is just 3% (Cancer Research UK statistics), and as a result pancreatic cancer is the 4th most common cause of cancer death in the UK and US.
  Precision Medicine DTP - Stromal transcriptomic signatures in prostate cancer metastasis and hormone therapy resistance
  Research Group: MRC Centre for Reproductive Health
  Dr B Qian, Prof H Y Leung, Dr A Sims, Prof P Wiklund
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. A tremendous amount of cancer ‘-omics’ data have been generated with the intention to stratify patients for personalized diagnosis and treatment.
  Precision Medicine DTP - Taming the Hippo in mesothelioma through proteogenomics
  Research Group: Centre for Inflammation Research
  Dr C G Hansen, Prof J Lehtio
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Pleural Mesothelioma is an asbestos-related cancer, which originates in the pleural lining of the lung and is characterized by a diverse phenotype.
  Precision Medicine DTP - Accurate methods for rare variant calling in low-coverage cancer exome sequencing data
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr G Stracquadanio, Dr G Sanguinetti
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. High-throughput sequencing technologies enabled the characterization of the genomic landscape of many tumours (1,2).
  Precision Medicine DTP - Connecting Molecular Profiles to Phenotype: A Proteomic Resource for Assigning Cell Cycle and Senescent States
  Research Group: Institute of Cell Biology
  Dr T Ly, Dr A Lindqvist
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. A hallmark of cancer is aberrant cell cycle control leading to pathological cell proliferation. Cell cycle progression is controlled by key kinases, such as cyclin-dependent kinases (CDKs) and polo-like kinases (PLKs).
  Precision Medicine DTP - Determining clinically significant early stage lung cancers from image analysis
  Dr W.H. Nailon
Application Deadline: 8 January 2020

Funding Type

PhD Type

Additional Supervisors. Dr Iain Philipps, Dr Duncan Mclaren & Dr Stephen Harrow. Background. Stereotactic Ablative Body Radiotherapy (SABR) is an image guided radiotherapy technique, used to deliver a curative treatment for early stage lung cancer.
  Precision Medicine DTP - Tumour exosome-functionalised magnetic nanoparticles for magnetic resonance imaging guided precision medicine and personalised breast cancer treatment
  Dr M Chen, Dr B Qian, Prof R Vellaisamy
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. One of the difficulties in cancer treatment is the tumour heterogeneity. Therefore, the conventional “one size fits all” approach and even the targeted therapeutics will not efficiently treat all cancer patients.
  Precision Medicine DTP - Analysis of intestinal metagenomes using ASAR
  Prof I Goryanin, Dr S Farrington, Prof M Dunlop
Application Deadline: 8 January 2020

Funding Type

PhD Type

Additional Supervisors. Dr Anatoly Sorokin & Dr Vidya Rajasekaran. Background. Understanding risk factors to Colorectal Cancer (CRC) can aid in its prevention.
  Precision Medicine DTP - Large-Scale Data-Driven Lung Cancer Diagnostics using Time-Resolved Fluorescence Spectroscopy (TRFS)
  Dr S Seth, Dr KD Dhaliwal, Dr M Khadem
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Pulmonary nodules are common, often incidental, findings on chest CT scans. The investigation of pulmonary nodules is, however, time-consuming and often leads to protracted follow-up with ongoing radiological surveillance.
  MRC Precision Medicine DTP: Applying machine learning models to genome data to understand the evolution of resistance from virus to cancer evolution
  Research Group: Institute of Infection, Immunity & Inflammation
  Prof D Robertson, Dr Ke Yuan
Application Deadline: 8 January 2020

Funding Type

PhD Type

Supervisors. Prof David L Robertson. Dr Ke Yuan. Project summary. Treatment of cancer and chronic infectious diseases often fail due to the evolution of resistance to therapy.
  MRC Precision Medicine DTP: Target autophagy and aberrant mitochondrial folate metabolism in leukaemic stem cells
  Research Group: Institute of Cancer Sciences
  Dr V Helgason, Dr A Vazquez
Application Deadline: 8 January 2020

Funding Type

PhD Type

Supervisors. Dr Vignir Helgason. Dr Alexei Vazquez. Dr Zuzana Brabcova. Project summary. Chronic myeloid leukaemia (CML) develops following a specific mutation in a single blood stem cell.
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