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Cancer / Oncology PhD Projects, Programs & Scholarships

We have 289 Cancer / Oncology PhD Projects, Programs & Scholarships

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  Clinical Research Fellow in Blood Cancer Research

Funding Type

PhD Type

We are looking for a keen and enthusiastic Clinical Research Fellow to join the blood cancer research group with the view to obtaining with a view to obtaining an MD or PhD.
  Bioinformatic identification of mechanisms of tumour development from cancer genome sequencing data
  Dr S Furney
Application Deadline: 14 October 2019

Funding Type

PhD Type

The aim of the project is to investigate the interaction between environmental exposures and genomic variation in tumour development.
  Role of the centrosome and cilia in development
  Dr C Wilkinson
Applications accepted all year round

Funding Type

PhD Type

My research interest lies in the roles of centrioles and associated proteins, as parts of the centrosome and cilium, in early vertebrate development, using zebrafish embryos as a model system.
  Early detection of colorectal cancer
  Dr V Li
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Vivian Li’s Group based at the Francis Crick Institute (the Crick).
  Investigating epigenetic diversity in cancer evolution
  Dr C Swanton, Dr P Van Loo
Application Deadline: 12 November 2019

Funding Type

PhD Type

The Van Loo and Swanton labs developed approaches to unravel the evolutionary history and subclonal architecture of cancer from DNA profiling data (1,2…
  Understanding interplay between genetic intra-tumour heterogeneity and the local tumour microenvironment
  Dr E Sahai
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Erik Sahai’s Group based at the Francis Crick Institute (the Crick). Intra-tumour heterogeneity represents a major challenge in the treatment of cancers.
  Using convolutional neural networks to distinguish between autophagy and related processes
  Dr R Beale
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Rupert Beale’s Group based at the Francis Crick Institute (the Crick).
  PhD for Clinicians (3 years)

Funding Type

PhD Type

 The Crick is a multi-disciplinary biomedical discovery research institute in central London dedicated to understanding the fundamental biology underlying health and disease.
  Department of Health Technology and Informatics

Funding Type

PhD Type

The Department of Health Technology and Informatics welcomes applications from high potential candidates with academic excellence, research ability and potential, and good communication, interpersonal and leadership abilities for full-time PhD study in Hong Kong through the Hong Kong PhD Fellowship Scheme (HKPFS) 2020/21.
  Characterising surface properties of protein biopharmaceutical molecules
  Dr A Golovanov, Dr J Warwicker
Applications accepted all year round

Funding Type

PhD Type

Protein biologicals have great potential for the effective treatment of a wide range of diseases. However, aggregation and instability are inherent issues with all protein pharmaceuticals, which is a problem that can limit their utility and developability.
  Design, Synthesis and Biological Evaluation of novel inhibitors of the JAK-STAT signalling pathway with potential application as immune oncology agents
  Dr R Whitehead, Dr K Finegan, Prof N Turner
Applications accepted all year round

Funding Type

PhD Type

Small molecule inhibitors of the JAK-STAT signalling pathway often possess interesting biological properties with many displaying potent anti-proliferative activity towards cancer cell lines.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
  Dr C Francavilla, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g.
  Proteomic analyses of adhesion signalling in cancer
  Prof M J Humphries
Applications accepted all year round

Funding Type

PhD Type

Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation.
  (MRC DTP) Using super-resolution microscopy to understand immune cell inhibitory receptors and develop novel immune therapies
  Prof D Davis, Dr J Honeychurch
Application Deadline: 15 November 2019

Funding Type

PhD Type

Super-resolution microscopy allows us to study immune cell activity in unprecedented detail. Recently, Davis’s research team has used these microscopes to study the changing arrangements of molecules on the surface of immune cells as they survey other cells for signs of disease.
  Exploiting tumour-promoting paracrine signals in solid cancers to turbocharge genetically redirected T cells
  Dr A Hurlstone, Prof R Edmondson
Applications accepted all year round

Funding Type

PhD Type

Adoptive cell therapy (ACT) using tumour infiltrating lymphocytes (TILs) or genetically redirected T cells are some of the most promising approaches to emerge recently for the treatment of metastatic disease.
  Virus pathogenesis: interplay between the unfolded protein response and innate immunity.
  Dr S-W Chan, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

The unfolded protein response (UPR) is a cellular homeostatic response in restoring endoplasmic reticulum balance upon stress conditions e.g.
  Linear Poisson Modelling Independent Component Analysis of DESI Mass Spectral Tissue Images
  Dr A McMahon, Dr N Thacker
Applications accepted all year round

Funding Type

PhD Type

Desorption Electrospray Ionisation - Mass Spectrometry Imaging (DESI – IMS) allows mass spectra to be acquired from an. array of.
  Use of highly multi-modal PET and MRI data as a predictive biomarker of the site of recurrence in neuro-oncology
  Dr R Hinz, Dr David Coope, Prof A Jackson
Applications accepted all year round

Funding Type

PhD Type

Primary brain tumour including glioblastoma (GBM), the most aggressive and most common form in adults, continue to have a socioeconomic impact that is disproportionate to the tumour frequency due to our inability to obtain a cure in the vast majority of adult sufferers.
  Analysis of the role of microRNAs in the regulation of NF-kappaB dynamics and function
  Prof M White, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

NF-κB is one of most important cell signalling systems in the body and controls inflammation and cell fate. NF-κB signalling involves complex dynamics involving oscillations of the NF-κB complex between the nucleus and cytoplasm in activated cells.
  Breast Cancer Omics and Modelling
  Dr C Francavilla, Prof R Breitling
Applications accepted all year round

Funding Type

PhD Type

Background and goals. Breast cancer is the major cause of death among women and 90% of deaths are caused by incurable metastasis.
  Deciphering a novel anti-ageing epigenetic programme
  Dr G Poulin, Prof A Sharrocks
Applications accepted all year round

Funding Type

PhD Type

Over two decades of intense research in the field of epigenetics have produced compelling evidence that chromatin modifications are crucial for processes such as DNA repair, transcription, splicing, mitosis, meiosis, and in the preservation of the epigenetic memory of cells.
  Microtubule motors in cell migration and integrin trafficking
  Prof V Allan, Prof P Woodman, Dr P Caswell
Applications accepted all year round

Funding Type

PhD Type

Cell migration is vital for the development and health of multicellular organisms. However, enhanced cell migration is also a hallmark of cancer cells, and contributes greatly to metastasis.
  Preparing the acid bath: how epidermal growth factor receptor (EGFR) controls its own down-regulation
  Prof P Woodman, Dr C Francavilla
Applications accepted all year round

Funding Type

PhD Type

Signalling by cell surface receptors determines nearly every aspect of the cell’s response to its environment. Endosomes are hubs for regulating these signalling pathways.
  Stress regulation of protein translation: role in cancer and neurodegeneration
  Dr A J Whitmarsh, Prof M Ashe
Applications accepted all year round

Funding Type

PhD Type

Cells are subjected to a range of stresses that include physical injury, changes in oxygen levels or temperature, nutrient deprivation, radiation and infection.
  Understanding mechanisms of Notch regulation and misregulation in endocytic pathway
  Dr M Baron, Dr R Clarke
Applications accepted all year round

Funding Type

PhD Type

Notch is a developmental signalling receptor with widespread and important roles in metazoan development and also in adult stem cell regulation.
  Understanding the gene regulatory landscape of embryonic stem cells and cancer cells
  Prof A Sharrocks, Prof M Rattray
Applications accepted all year round

Funding Type

PhD Type

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity.
  (MRC DTP) The role of the lung microenvironment in regulating metastatic colonisation by breast cancer
  Dr R Clarke, Dr Ciara O'Brien, Dr R Eyre
Application Deadline: 15 November 2019

Funding Type

PhD Type

The metastatic spread of breast cancer cells and their colonisation of important organs such as the lungs is the cause of death in 95% of breast cancer.
  Characterizing the heterogeneity of stem cells in the normal breast and breast tumours
  Dr A Ucar, Prof K R Brennan
Applications accepted all year round

Funding Type

PhD Type

Tissue-restricted stem cells are crucial in supporting the development and maintenance of normal tissues. This is also true for tumours, as only a small population of tumour cells, which are known as cancer stem cells, have the unique stemness features and tumour-initiating capacity.
  Characterizing the in vivo functions of P-Rex1 in breast development and tumourigenesis
  Dr A Ucar, Prof K R Brennan, Dr A Malliri
Applications accepted all year round

Funding Type

PhD Type

Breast cancer is the most common cancer in the UK with a lifetime risk of 1-in-8 for women and accounts for 12,000 deaths annually.
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