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We have 44 Cancer Biology (cell therapy) PhD Projects, Programmes & Scholarships for Self-funded Students

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Cancer Biology (cell therapy) PhD Projects, Programmes & Scholarships for Self-funded Students

We have 44 Cancer Biology (cell therapy) PhD Projects, Programmes & Scholarships for Self-funded Students

Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

ROLE OF FOXO1 TRANSCRIPTION FACTOR IN B-CELL MALIGNANCIES

The project is focused on FoxO1 transcription factor and its role in the pathophysiology of chronic lymphocytic leukemia (CLL). Although the therapy of CLL has made several remarkable improvements, the disease still remains incurable. Read more

Nanoparticle synthesis and application in magnetic field hyperthermia for cancer therapy

  Research Group: Chemistry and Biosciences
Magnetic field hyperthermia (MFH) is currently undergoing clinical trials for use in humans. The research to date has shown the effectiveness of the approach in cells and animal models and the initial results from human trials are promising. Read more

Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more

PhD position in cell biology and inflammation in plasma-treated diseased keratinocytes

Short overview of PlasmACT. The PlasmACT network brings together 5 beneficiaries and 10 associated partners, located in 5 different countries (Germany, France, Netherlands, Belgium, and Luxembourg). Read more

Genomic actions of RAR and VDR ligands

The Doctoral Candidate (DC) will determine whether the combination of RARγ antagonist and VDR agonist is suitable as a differentiation therapy against acute myeloid leukaemia (AML). Read more

Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more

Cancer: Repurposing drugs as new treatments for breast cancer

Breast cancer (BC) is the most common cancer, with over 1 million new cases diagnosed worldwide each year. For some types of BC, hormonal treatments have been very effective but one particular BC subtype, triple negative breast cancer (TNBC), is highly aggressive and lacks a targeted therapy. Read more

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