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University of Birmingham Cancer / Oncology PhD Projects, Programs & Scholarships

We have 20 University of Birmingham Cancer / Oncology PhD Projects, Programs & Scholarships

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  Characterisation of novel human disease proteins involved in chromosomal instability.
  Prof G Stewart, Dr R J A Grand
Application Deadline: 4 October 2019

Funding Type

PhD Type

Genome instability is a fundamental feature of cancer and can arise via many different pathological mechanisms.
  The Role of LIM Domain Only Proteins in Neuroblastoma
  Dr M Hoogenkamp
Applications accepted all year round

Funding Type

PhD Type

Person Specification. An Upper Second Class Honours Degree (or equivalent) in a relevant study or Master’s degree is expected. Prior experience in cell and molecular biology is an advantage.
  Analysing immune responses to metastatic ovarian tumours to identify therapeutic targets
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Investigating how ovarian tumours avoid immune responses in cancer patients
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Determining the translational potential of the highly phosphorylated proto-oncogene PBF
  Dr V Smith
Applications accepted all year round

Funding Type

PhD Type

In order to translate the many molecular alterations now detectable in human tumours into effective clinical management we need to fully understand their impact on tumour biology.
  Development of novel artificial intelligence algorithms for network wide metabolic flux analysis with stable isotope tracers
  Dr C Ludwig, Dr S He
Applications accepted all year round

Funding Type

PhD Type

The efficient function of the metabolic network in eukaryotic cells relies on its separation into a number of closely-linked but metabolically distinct compartments.
  Metabolic control of T cell function
  Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Current research interests in Sarah Dimeloe’s lab focus on the metabolism and interlinked immune function of T lymphocytes in health and disease.
  Polo-like kinase inhibitors for targeted therapy in adrenocortical carcinoma
  Dr C L Ronchi, Dr P Foster
Applications accepted all year round

Funding Type

PhD Type

Adrenocortical carcinoma (ACC) is a rare cancer with a generally poor prognosis and partially unknown pathogenesis.
  Repairing DNA Damage in Response to BRAF Mutation
  Dr C McCabe, Prof G Stewart
Applications accepted all year round

Funding Type

PhD Type

We are the leading thyroid cancer research group in the UK; we work on other neoplasias as well, including breast and head and neck etc.
  Targeting steroid metabolism to block colorectal cancer proliferation
  Dr P Foster, Dr L Cox
Applications accepted all year round

Funding Type

PhD Type

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
  BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions.
  Epitranscriptomic mechanisms in the maternal to zygotic transition of vertebrate embryos
  Dr M Soller, Prof F Mueller
Applications accepted all year round

Funding Type

PhD Type

Most mRNAs contain modified nucleotides in mRNA, but we know very little about their function (Haussmann et al, 2016, Dezi et al, 2016, Roignant and Soller, 2017).
  mRNA epigenetics: Charaterization of a novel layer of gene regulation for essential brain functions
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr PG Grzechnik
Applications accepted all year round

Funding Type

PhD Type

For over 40 years we know about modified nucleotides in mRNA, but the functions for these essential modifications are largely elusive.
  Statistical and Molecular Genetics of Complex Traits
  Prof Z Luo
Applications accepted all year round

Funding Type

PhD Type

Most characters of any living organism are polygenically controlled and environmentally modified, including those threatening human health and those important in breeding for high yield, better quality and improved adaption of animals, plants and microbes.
  Understanding the mechanism of action of ferro-nucleobase analogues
  Dr N J Hodges
Applications accepted all year round

Funding Type

PhD Type

Through collaboration with Professor Jim Tucker (School of Chemistry) we are studying the cellular effects of a novel DNA base analogues based on the organometallic compound ferrocene.
  Understanding the role of the globin cytoglobin in cancer cell drug resistance
  Dr N J Hodges
Applications accepted all year round

Funding Type

PhD Type

Cytoglobin is related to haemoglobin and myoglobin but has a very poorly understood biological function. Work in our lab has shown that expression of cytoglobin in cancer cells alters mitochondrial function and affords protection from anti-cancer drugs including cisplatin.
  Dynamic interplay of cell shape and tumour evolution
  Dr F Spill, Prof I Tomlinson
Applications accepted all year round

Funding Type

PhD Type

Tumour cells are long known to appear in vastly diverse shapes, both across patients and within a single tumour. This is in stark contrast to the regularity of cell shapes of healthy epithelial tissues from which most tumours originate.
  Mathematical Modelling of Cancer-Cell Transmigration Through Blood Vessels
  Dr F Spill
Applications accepted all year round

Funding Type

PhD Type

Cancer rarely kills through the primary tumour in which cancer arises, e.g. the prostate in prostate cancer. Instead, cancer cells may travel through the vasculature and colonialize distant organs – a process termed metastasis.
  Delay to diagnosis and treatment in pancreatic cancer with patients, caregivers and healthcare professionals
  Prof A Topping
Applications accepted all year round

Funding Type

PhD Type

Applications are invited for a 3-year full time self-funded PhD Studentship (part time would be considered). Patients with pancreatic cancer are commonly diagnosed with advanced disease.
  Peer led storytelling intervention for individuals with cancer
  Dr A Soundy
Applications accepted all year round

Funding Type

PhD Type

The most recent developments in my research is the establishment and benefits of story telling for people with cancer. We have developed an intervention training package for health care professionals that needs testing.
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