Summary. Tackling eating disorders is of growing importance in society, with increasing numbers of children and young people referred to eating disorder services. Read more
Summary. Huntington's disease (HD) is an inherited disorder that causes specific neurons in the brain to die. HD patients develop uncontrollable movements as well as cognitive and sleep problems, and there is currently no effective treatment. Read more
Summary. In mice and humans loss-of-function of the steroid sulfatase (STS) enzyme results in inattention but enhanced motor response inhibition; we aim to understand the neurobiology underlying this dissociation using a new mouse model. Read more
Summary. There is no licenced vaccine against Staphylococcus aureus which produces life-threatening bloodstream infections ("bacteraemia") and has evolved antibiotic-resistant strains. Read more
Summary. Human cytomegalovirus (HCMV) is the leading infectious cause of congenital birth defects and causes severe disease immunosuppressed individuals. Read more
Summary. Mood disorders (MDs), e.g. depression, affect over one billion people worldwide. MDs show a bidirectional relationship with systemic inflammation, a key component in the pathophysiology of autoimmune disorders (ADs), e.g. Read more
Fungal infections are a major threat to public health as they are becoming increasingly resistant to treatment. Only four classes of antifungals are available, with few candidates in the clinical pipeline. Read more
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