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Cell Biology / Development (amyloid) PhD Projects, Programs & Scholarships

We have 8 Cell Biology / Development (amyloid) PhD Projects, Programs & Scholarships

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  An integrated approach to the study of cellular interactions with amyloid
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford
Applications accepted all year round

Funding Type

PhD Type

The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
  Characterisation of the neuronal receptor for soluble amyloid precursor protein: a route to new therapeutic targets for Alzheimer’s disease
  Prof N Hooper, Prof M J Humphries
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease (AD) is the commonest form of dementia for which currently there is no means of stopping or even slowing the disease.
  Ca2+ signalling in neurodegeneration and Alzheimer’s disease
  Research Group: School of Biology
  Prof I A Hope
Applications accepted all year round

Funding Type

PhD Type

Human variants of the ryanodine receptor, the main intracellular calcium ion channel, could be responsible for Alzheimer’s disease.
  Are Tau fibrils induced by phosphorylation and the interaction with 14-3-3 proteins relevant for Alzheimer disease?
  Dr J Hritz, Dr JN Nováček, Dr J Pribyl
Application Deadline: 20 February 2020

Funding Type

PhD Type

Several neurodegenerative diseases are associated with the formation of fibrous protein aggregates. The fibrillization of amyloid beta peptide into amyloid plaques and the agregation of hyperphosphorylated tau protein into neurofibrillar tangles are main neuropatological signs of Alzheimer disease.
  Role of phosphorylated 14-3-3 proteins
  Dr J Hritz, Assoc Prof V Bryja
Application Deadline: 1 February 2020

Funding Type

PhD Type

14-3-3 proteins play key role in the neurobiochemistry of brain and are also associated with neurodegenerative amyloid diseases such as Alzheimer and Parkinson disease.
  (BBSRC DTP) Selective knockdown of proinflammatory microRNAs to tackle neurodegeneration and cognitive decline: myth or reality?
  Dr E Bichenkova, Prof J Neill, Dr F Roncaroli, Prof D Clarke
Application Deadline: 31 January 2020

Funding Type

PhD Type

Neurodegenerative diseases (e.g. multiple and amyotrophic lateral sclerosis, Alzheimer’s and Parkinson’s diseases) have tremendous psychological, clinical and social impact, which becomes increasingly challenging in the global trend of population aging.
  Analysing the factors that regulate expression of blood-brain barrier drug transporter proteins
  Dr J L Penny, Dr C Demonacos
Applications accepted all year round

Funding Type

PhD Type

In order to treat diseases associated with the central nervous system (CNS), e.g. cancer, Parkinson’s disease, depression, it is essential for therapeutic drugs to be able to penetrate into the brain.
  Understanding cellular and network mechanisms underlying memory dysfunction in Alzheimer’s disease
  Research Group: Centre for Clinical Brain Sciences
  Dr S Wang, Prof S Grant
Application Deadline: 29 February 2020

Funding Type

PhD Type

Memory impairment is among the early signs in Alzheimer’s disease (AD) that significantly affects daily function. It is vital to understand how neurons encoding memory (i.e.
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