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We have 10 Cell Biology (antibodies) PhD Projects, Programmes & Scholarships

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Cell Biology (antibodies) PhD Projects, Programmes & Scholarships

We have 10 Cell Biology (antibodies) PhD Projects, Programmes & Scholarships

Investigating the role of SUMOylation in meiotic recombination and chromosome segregation in Arabidopsis

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
Post-translational modifications of proteins such as phosphorylation, methylation and acetylation have been extensively studied in eukaryotes and now the Small Ubiquitin modifier (SUMO) is gaining attention for its importance in fundamental biological roles. Read more

The BCAT1 CXXC Motif and Oncogenesis in Acute Myeloid Leukaemia

The BCAT1 gene is implicated in the pathogenesis of many cancer types, including acute myeloid leukaemia (AML)1–4. Recently, our group identified a novel antioxidant role for BCAT1 in AML cells5. Read more

Role of BTG1 and BTG2 in acute lymphocytic leukaemia and diffuse large B-cell lymphoma

Acute lymphocytic leukaemia (ALL) and diffuse large B-cell lymphoma (DLBCL) is often associated with small deletions of or point mutations in the highly related BTG1 or BTG2 genes. Read more

Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Immunotherapy: Killing Cancer using Dead Virus

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more
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