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Cell Biology / Development (antibody) PhD Projects, Programs & Scholarships

We have 13 Cell Biology / Development (antibody) PhD Projects, Programs & Scholarships

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We have 13 Cell Biology / Development (antibody) PhD Projects, Programs & Scholarships

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Cancer therapy endocytosis

This is a project which aims to investigate how tumours and normal tissue internalise drugs such as cancer therapy antibodies in real in vivo models and in patients. Read more

Investigating the effects of inflamm-aging on the safety and efficacy of monoclonal antibody based therapies

Our understanding of the immune response in the elderly is still in its infancy. Now, more than ever we need to understand the basic principles of immune response as the environment alters our immune system and the particles it sees. Read more

Precise, peptide-directed loading of drugs onto therapeutic antibodies for targeted imaging and treatment of tumors.

The PhD project aims to develop a non-covalent technology for loading small molecules and therapeutic enzymes onto monoclonal antibodies thus addressing issues in preparations of antibody-drug conjugates, such as poor yields and non-specific conjugation of the drugs resulting in compromised immunoaffinity. Read more

A new bioconjugation agent for RNA analysis.

This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. For further details. Read more

Genome Diversification in Cancer and Adaptive Immunity

Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more

Genome Diversification in Cancer and Adaptive Immunity

Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more

Is there a Role for Activated Akt in Palatogenesis?

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

(BBSRC DTP) Understanding how macrophages respond to damage-derived inflammatory signals

Innate immune recognition of danger signals is an important mechanism that protect us against infection and injury. ATP is an important danger signal released from infected or damaged cells and its extracellular presence alerts macrophages of impending danger. Read more

EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more
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